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肝门部胆管癌患者右半肝切除术后复发性急性门静脉血栓形成伴严重腹部感染:一例报告及文献复习

Recurrent acute portal vein thrombosis with severe abdominal infection after right hemihepatectomy in a patient with perihilar cholangiocarcinoma: A case report and literature review.

作者信息

Deng Qingsong, He Minglian, Yang Yuehua, Ou Yanjiao, Cao Yong, Zhang Leida

机构信息

Army Institute of Hepatobiliary Surgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China.

Clinical Research Commissioner, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China.

出版信息

Int J Surg Case Rep. 2022 Apr;93:106904. doi: 10.1016/j.ijscr.2022.106904. Epub 2022 Mar 1.

Abstract

INTRODUCTION AND IMPORTANCE

Portal vein thrombosis (PVT) is a serious complication after hepatobiliary-pancreatic surgery. There have been few studies on recurrent PVT after hepatectomy for perihilar cholangiocarcinoma.

CASE PRESENTATION

We report the case of a 66-year-old woman who was diagnosed with perihilar cholangiocarcinoma and treated with right hemihepatectomy. On the sixth day, the patient developed acute portal vein thrombosis, and emergency portal vein incision and surgical thrombectomy were performed. On the seventh day after thrombectomy, the patient developed acute portal vein thrombosis again, and portal vein thrombectomy+portal vein bridging was performed again. There was still thrombosis after the operation. The patient was then treated with superior mesenteric arteriography + indirect portal vein catheterization thrombolysis and local thrombolysis + anticoagulation and systemic anticoagulation therapy. The patient had a complicated abdominal infection. The total hospital stay was 84 days. There was no thrombosis in the portal vein at discharge.

CLINICAL DISCUSSION

Although the procedure was carefully performed with a preoperative plan and fine intraoperative vascular anastomosis, postoperative PVT occurred. There are many factors of portal vein thrombosis, and there are many treatment methods.

CONCLUSION

PVT often develops in patients with liver cirrhosis postoperatively and after liver transplantation. Recurrent PVT after hepatectomy for perihilar cholangiocarcinoma is a rare complication.

摘要

引言与重要性

门静脉血栓形成(PVT)是肝胆胰手术后的一种严重并发症。关于肝门部胆管癌肝切除术后复发性PVT的研究较少。

病例报告

我们报告一例66岁女性患者,被诊断为肝门部胆管癌并接受了右半肝切除术。术后第6天,患者发生急性门静脉血栓形成,遂行急诊门静脉切开取栓术。取栓术后第7天,患者再次发生急性门静脉血栓形成,再次行门静脉取栓术+门静脉搭桥术。术后仍有血栓形成。随后患者接受了肠系膜上动脉造影+间接门静脉置管溶栓及局部溶栓+抗凝和全身抗凝治疗。患者发生了复杂的腹腔感染。住院总天数为84天。出院时门静脉无血栓形成。

临床讨论

尽管手术严格按照术前计划进行,术中血管吻合精细,但术后仍发生了PVT。门静脉血栓形成的因素众多,治疗方法也多种多样。

结论

PVT常发生于肝硬化患者术后及肝移植后。肝门部胆管癌肝切除术后复发性PVT是一种罕见的并发症。

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