Fenerbahçe University, Faculty of Health Sciences, Department of Midwifery, Istanbul/Turkey.
Zeynep Kamil Woman and Child Diseases Education and Research Hospital, Gynecology and Obstetrics Clinic, Istanbul/Turkey.
Malawi Med J. 2021 Dec;33(4):300-302. doi: 10.4314/mmj.v33i4.12.
Castleman's disease was first described by Castleman et al. in 1956 as a non-lymphoproliferative disease.1 Castleman's disease (CD), or angiofollicular lymphoid hyperplasia, is a rare disease with unknown etiology that can be easily misdiagnosed as lymphoma, neoplasm, or infection. Very few cases of pelvic origin and observed in pregnancy have been reported in the literature and are usually asymptomatic. Preoperative diagnosis is very difficult due to nonspecific imaging findings and rarity; most cases are diagnosed based on postoperative pathological examination. In this paper, a case of a 36-year-old pregnant woman suspected of adnexal origin in the uterine posterolateral, which was detected incidentally by ultrasound, was presented. The patient underwent a successful mass excision. Pathology of mass observed to be in the pelvic retroperitoneum was detected as localized unicentric and hyaline vascular CD. The study was conducted to discuss the diagnostic tools and perioperative management needed to identify the retroperitoneal unicentric Castleman case.
卡斯尔曼病（Castleman's disease，CD），又称血管滤泡性淋巴组织增生症，是一种病因不明的罕见疾病，易误诊为淋巴瘤、肿瘤或感染。文献中报道的盆腔来源且发生于妊娠的非常少，且通常无症状。由于影像学表现不具特异性和罕见性，术前诊断非常困难；大多数病例是基于术后病理检查诊断的。本文报道了 1 例 36 岁孕妇，超声偶然发现子宫后外侧附件来源的肿块，行肿块切除术，术后病理诊断为局限型透明血管型 CD。该研究旨在探讨识别腹膜后局灶型 CD 病例所需的诊断工具和围手术期管理。卡斯尔曼等人于 1956 年首次描述了该病，当时将其归类为非淋巴组织增生性疾病。
