Goodyer Elliot, Mah Jasmine C, Rangan Apoorva, Chitalu Petronella, Andrew Melissa K, Searle Samuel D, Davis Daniel, Tsui Alex
MRC Unit for Lifelong Health and Ageing at UCL, London, UK.
Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.
Aging Med (Milton). 2022 Mar;5(1):10-16. doi: 10.1002/agm2.12200. Epub 2022 Feb 27.
Frailty and socioeconomic position (SEP) are well-established determinants of health. However, we know less about the contributions of frailty and SEP in older adults, especially in acute settings. We set out to answer how frailty and SEP might influence health outcomes in older people, comparing a population sample and patients managed by a speciality acute frailty service.
We used the Delirium and Population Health Informatics Cohort, a population sample of 1510 individuals aged ≥70 years from the London Borough of Camden and 1750 acute frailty patients. SEP was determined using the Index of Multiple Deprivation. Linear and Cox proportional hazard regression models were conducted to assess SEP on frailty, readmission, and mortality outcomes.
In the population sample, SEP was significantly associated with frailty and mortality with successive increases in rate of death for each IMD quintile (HR = 1.28, 95% CI 1.11 to 1.49, < 0.005). Increasing SEP, age, and admission status among hospitalized individuals were associated with greater frailty. For individuals seen by the speciality frailty service, SEP was not associated with frailty, mortality, or readmission.
When older people experience acute illness severe enough to require secondary care, particularly specialist services, this overcomes any prior advantages conferred by a higher SEP.
虚弱和社会经济地位(SEP)是公认的健康决定因素。然而,我们对老年人中虚弱和SEP的作用了解较少,尤其是在急性病环境中。我们着手研究虚弱和SEP如何影响老年人的健康结局,比较了一个人群样本和由专科急性虚弱服务机构管理的患者。
我们使用了谵妄与人群健康信息队列,该队列包括来自伦敦卡姆登区的1510名年龄≥70岁的人群样本以及1750名急性虚弱患者。使用多重剥夺指数来确定SEP。进行线性回归和Cox比例风险回归模型,以评估SEP对虚弱、再入院和死亡率结局的影响。
在人群样本中,SEP与虚弱和死亡率显著相关,随着每个多重剥夺指数五分位数的死亡发生率依次增加(风险比=1.28,95%置信区间为1.11至1.49,P<0.005)。住院个体中SEP的增加、年龄的增长和入院状态与更高的虚弱程度相关。对于由专科虚弱服务机构诊治的个体,SEP与虚弱、死亡率或再入院无关。
当老年人经历严重到需要二级护理,特别是专科服务的急性疾病时,这会克服先前较高SEP所带来的任何优势。