Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.
Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada.
BMC Geriatr. 2020 Oct 7;20(1):393. doi: 10.1186/s12877-020-01801-7.
Frailty is increasingly recognized as an important construct which has health implications for older adults. The Clinical Frailty Scale (CFS) is a judgement-based frailty tool that evaluates specific domains including comorbidity, function, and cognition to generate a frailty score ranging from 1 (very fit) to 9 (terminally ill). The aim of this scoping review is to identify and document the nature and extent of research evidence related to the CFS.
We performed a comprehensive literature search to identify original studies that used the Clinical Frailty Scale. Medline OVID, Scopus, Web of Science, CINAHL, PsycINFO, Cochrane Library and Embase were searched from January 2005 to March 2017. Articles were screened by two independent reviewers. Data extracted included publication date, setting, demographics, purpose of CFS assessment, and outcomes associated with CFS score.
Our search yielded 1688 articles of which 183 studies were included. Overall, 62% of studies were conducted after 2015 and 63% of the studies measured the CFS in hospitalized patients. The association of the CFS with an outcome was examined 526 times; CFS was predictive in 74% of the cases. Mortality was the most common outcome examined with CFS being predictive 87% of the time. CFS was associated with comorbidity 73% of the time, complications 100%, length of stay 75%, falls 71%, cognition 94%, and function 91%. The CFS was associated with other frailty scores 94% of the time.
This scoping review revealed that the CFS has been widely used in multiple settings. The association of CFS score with clinical outcomes highlights its utility in the care of the aging population.
虚弱日益被认为是一个重要的概念，对老年人的健康有影响。临床虚弱量表（CFS）是一种基于判断的虚弱工具，评估包括合并症、功能和认知在内的特定领域，以生成从 1（非常健康）到 9（生命垂危）的虚弱评分。本范围综述的目的是确定和记录与 CFS 相关的研究证据的性质和范围。
我们进行了全面的文献检索，以确定使用临床虚弱量表的原始研究。从 2005 年 1 月至 2017 年 3 月，在 OVID Medline、Scopus、Web of Science、CINAHL、PsycINFO、Cochrane 图书馆和 Embase 上搜索了文章。由两名独立的审查员进行筛选。提取的数据包括出版日期、地点、人口统计学、CFS 评估的目的以及与 CFS 评分相关的结果。
我们的搜索结果产生了 1688 篇文章，其中 183 篇研究被纳入。总体而言，62%的研究是在 2015 年之后进行的，63%的研究是在住院患者中测量 CFS。CFS 与结果的关联共被检查了 526 次；在 74%的情况下，CFS 是可预测的。死亡率是最常见的检查结果，CFS 的预测率为 87%。CFS 与合并症的关联时间为 73%，并发症为 100%，住院时间为 75%，跌倒为 71%，认知为 94%，功能为 91%。CFS 与其他虚弱评分的关联时间为 94%。
本范围综述表明，CFS 已在多个环境中广泛使用。CFS 评分与临床结果的关联突出了其在老龄化人口护理中的效用。
