Aurangabadkar Gaurang M, Lanjewar Ajay V, Jadhav Ulhas S, Ali Saood N, Wagh Pankaj B
Respiratory Medicine, Jawaharlal Nehru Medical College, Wardha, IND.
Cureus. 2022 Feb 2;14(2):e21828. doi: 10.7759/cureus.21828. eCollection 2022 Feb.
Pulmonary hypertension (PH) is frequently underdiagnosed and under-evaluated in chronic obstructive pulmonary diseases (COPD) patients. As PH is linked to a high rate of mortality from disease-related complications like cor pulmonale, it is critical to have a unified approach to diagnosing and treating it with the aim of improving the patient's quality of life and prognosis in terms of therapeutic considerations. Early identification of this comorbidity in patients with COPD can lead to early initiation of treatment and better prognostic implications. This study was undertaken with the aim of estimating the prevalence of PH in COPD as well as assessing any statistically significant associations between the severity of PH and the severity of COPD.
This was an observational study undertaken at the Department of Respiratory Medicine, Acharya Vinoba Bhave Rural Hospital (AVBRH) in Wardha, Maharastra, India, from August 2019 to September 2021. A total of 100 patients diagnosed with COPD on the basis of spirometry were evaluated with two-dimensional (2D) echocardiography to screen for echocardiographic signs and evidence of PH and severity staging of PH if present.
In our study, out of 100 diagnosed cases of COPD, the prevalence of PH was found to be 40% (40 patients) and amongst these, mild, moderate, and severe PH was seen in 26 patients (26%), nine patients (9%), and five patients (5%), respectively. The frequency of PH in moderate COPD was 25% and in severe COPD was 51.5%.
PH was found in almost half the COPD patients in the study. Also, the degree and frequency of PH increased with the increase in COPD severity and this was found to be statistically significant.
慢性阻塞性肺疾病(COPD)患者的肺动脉高压(PH)常常未得到充分诊断和评估。由于PH与诸如肺心病等疾病相关并发症的高死亡率相关,因此从治疗角度出发,采用统一的方法来诊断和治疗PH对于改善患者生活质量和预后至关重要。在COPD患者中早期识别这种合并症可促使早期开始治疗并带来更好的预后影响。本研究旨在估计COPD中PH的患病率,并评估PH严重程度与COPD严重程度之间是否存在任何具有统计学意义的关联。
这是一项于2019年8月至2021年9月在印度马哈拉施特拉邦沃尔哈市阿查里亚·维诺巴·巴韦农村医院(AVBRH)呼吸内科进行的观察性研究。对总共100例根据肺功能测定诊断为COPD的患者进行二维(2D)超声心动图评估,以筛查PH的超声心动图征象和证据,以及若存在PH时的严重程度分期。
在我们的研究中,100例确诊的COPD病例中,PH的患病率为40%(40例患者),其中轻度、中度和重度PH分别见于26例患者(26%)、9例患者(9%)和5例患者(5%)。中度COPD中PH的发生率为25%,重度COPD中为51.5%。
在该研究中,几乎一半的COPD患者存在PH。此外,PH的程度和发生率随COPD严重程度的增加而升高,且这具有统计学意义。