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慢性阻塞性肺疾病与心脏共病:一项横断面研究。

Chronic obstructive pulmonary disease and cardiac comorbidities: A cross-sectional study.

作者信息

Kaushal Mohit, Shah Parth S, Shah Arti D, Francis Stani A, Patel Nihar V, Kothari Kavit K

机构信息

Department of Respiratory Medicine, Smt. B. K. Shah Medical Institute and Research Centre, Vadodara, Gujarat, India.

出版信息

Lung India. 2016 Jul-Aug;33(4):404-9. doi: 10.4103/0970-2113.184874.

Abstract

INTRODUCTION

Chronic obstructive pulmonary disease (COPD) is a global health issue with cigarette smoking being an important risk factor. COPD affects pulmonary blood vessels, right ventricle, as well as left ventricle leading to the development of pulmonary hypertension (PH), cor-pulmonale (COR-P), right and left ventricular dysfunction. Echocardiography provides a rapid, noninvasive, portable, and accurate method to evaluate cardiac functions. Early diagnoses and intervention for cardiac comorbidities would reduce mortalities.

MATERIALS AND METHODS

A cross-sectional study. Total 50 patients of moderate to severe COPD according to GOLD guidelines were taken from Department of Respiratory Medicine, Smt. B. K. Shah Medical Institute and Research Centre, Vadodara. All patients underwent investigations such as chest X-ray PA view, ECG, and spirometry followed by two-dimensional echocardiography.

RESULTS

We investigated 49 males and 1 female patients ranging from 35 to 80 years of age. Twenty-nine individuals were of moderate COPD and twenty-one of severe COPD. Of these cases 29 had left ventricular diastolic dysfunction (LVDD) changes, 24 were diagnosed with PH and 16 had changes of COR-P. The study showed the linear relation between the severity of LVDD, PH, and COR-P with the severity of COPD.

CONCLUSION

Our study put emphasis on early cardiac screening of all COPD patients which will be helpful in the assessment of the prognosis and will further assist in identifying the individuals likely to suffer increase morbidity and mortality.

摘要

引言

慢性阻塞性肺疾病(COPD)是一个全球性的健康问题,吸烟是其重要的危险因素。COPD会影响肺血管、右心室以及左心室,导致肺动脉高压(PH)、肺心病(COR-P)以及左右心室功能障碍。超声心动图提供了一种快速、无创、便携且准确的评估心脏功能的方法。对心脏合并症进行早期诊断和干预可降低死亡率。

材料与方法

一项横断面研究。根据GOLD指南,从瓦多达拉市Smt. B. K. Shah医学研究所和研究中心呼吸内科选取了50例中重度COPD患者。所有患者均接受了胸部X线正位片、心电图、肺功能检查,随后进行二维超声心动图检查。

结果

我们调查了49例男性和1例女性患者,年龄在35至80岁之间。其中29例为中度COPD,21例为重度COPD。在这些病例中,29例有左心室舒张功能障碍(LVDD)改变,24例被诊断为PH,16例有COR-P改变。研究表明LVDD、PH和COR-P的严重程度与COPD的严重程度呈线性关系。

结论

我们的研究强调对所有COPD患者进行早期心脏筛查,这将有助于评估预后,并进一步协助识别可能增加发病率和死亡率的个体。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9e5/4948228/47aa89e3cdfc/LI-33-404-g002.jpg

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