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腹腔镜袖状胃切除术后对高危重度肥胖患者进行常规早期计算机断层扫描检查可有效诊断出血或血肿,但不能诊断吻合口漏:一项前瞻性研究。

Routine Early Computed Tomography Scanner After Laparoscopic Sleeve Gastrectomy in High-Risk Severely Obese Patients Is Effective for Bleeding or Hematoma Diagnosis but not for Staple-Line Leak Detection: a Prospective Study.

机构信息

Department of Minimally Invasive Digestive Surgery, Antoine-Béclère Hospital, AP-HP, F-92140, Clamart, France.

Paris-Saclay University, F-91405, Orsay, France.

出版信息

Obes Surg. 2022 May;32(5):1624-1630. doi: 10.1007/s11695-022-05997-y. Epub 2022 Mar 15.

Abstract

PURPOSE

Laparoscopic sleeve gastrectomy (LSG) is the most frequently performed bariatric procedure worldwide. Postoperative staple-line leak and intraabdominal hemorrhage can increase associated morbidity and mortality. The value of routine early computed tomography (CT) scanner examination in the early diagnosis of complications in high-risk severely obese patients undergoing LSG is studied.

METHODS

This was a prospective, non-randomized study including all patients undergoing LSG in our department from 2014 to 2020. Patients presenting at least one potential risk factor for postoperative gastric leak and bleeding (as defined by the current literature) were included. Primary endpoint was the efficacy of postoperative day (POD) 2 CT-scanner examination in diagnosing these complications.

RESULTS

One thousand fifty-one high-risk patients were included. Median age was 44 years. Early postoperative surgical complications occurred in 48 patients (4.5%): 25 (2.3%) intraabdominal hemorrhage and 23 (2.2%) staple-line leak. Early CT-scanner detected intraabdominal bleeding or hematoma in 22/25 patients, with 95.6% sensitivity (Youden's index = 0.95), while specificity was 100%, positive predictive value (PPV) 100%, and negative predictive value (NPV) 99.9%. Sensitivity of early postoperative CT-scanner was 43.4% (10/23 patients; Youden's index = 0.43) for staple-line leak detection, with specificity of 100%, PPV 100%, and NPV 98.7%.

CONCLUSION

POD 2 CT-scanner in high-risk severely obese patients undergoing LSG is an excellent tool for early diagnosis of intraabdominal hemorrhage, but sensitivity remains low for staple-line leak detection. Close postoperative clinical follow-up of these patients is essential and any suspicion of postoperative surgical complication should motivate the performance of a CT-scanner.

摘要

目的

腹腔镜袖状胃切除术(LSG)是全球应用最广泛的减重手术。术后吻合口漏和腹腔内出血会增加相关发病率和死亡率。本研究旨在探讨在接受 LSG 的高危重度肥胖患者中,术后第 2 天行常规早期计算机断层扫描(CT)检查对早期诊断并发症的价值。

方法

这是一项前瞻性、非随机研究,纳入了 2014 年至 2020 年期间在我科接受 LSG 的所有患者。纳入了至少存在一项术后胃漏和出血潜在危险因素(如当前文献所定义)的患者。主要终点是术后第 2 天行 CT 扫描检查对这些并发症的诊断效果。

结果

共纳入了 1051 例高危患者,中位年龄为 44 岁。术后早期发生手术并发症 48 例(4.5%):25 例(2.3%)腹腔内出血,23 例(2.2%)吻合口漏。早期 CT 扫描发现 25 例患者中有 22 例存在腹腔内出血或血肿,敏感性为 95.6%(Youden 指数=0.95),特异性为 100%,阳性预测值(PPV)为 100%,阴性预测值(NPV)为 99.9%。早期 CT 扫描对吻合口漏的敏感性为 43.4%(10/23 例;Youden 指数=0.43),特异性为 100%,PPV 为 100%,NPV 为 98.7%。

结论

在接受 LSG 的高危重度肥胖患者中,术后第 2 天行 CT 扫描是早期诊断腹腔内出血的极好工具,但对吻合口漏的敏感性仍然较低。对这些患者进行密切的术后临床随访至关重要,任何怀疑术后手术并发症的迹象都应促使进行 CT 扫描。

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