Department of Internal Medicine, Division of Hematology.-Medical Oncology, Dr. Cipto Mangunkusumo General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia.
Niger J Clin Pract. 2022 Mar;25(3):373-375. doi: 10.4103/njcp.njcp_1401_21.
Chronic Myeloid Leukemia (CML) is one of the myeloproliferative disorders characterized by Philadelphia chromosome presence. Contrary to Western countries, most CML patients in Indonesia present symptoms with splenomegaly as the most common finding. It is rare to find asymptomatic CML patients. We present a case of asymptomatic chronic-phase chronic myeloid leukemia BCR-ABL (+) without splenomegaly who achieved a hematologic and molecular response to imatinib.
慢性髓性白血病（CML）是一种骨髓增生性疾病，其特征是费城染色体的存在。与西方国家不同，印度尼西亚大多数 CML 患者表现出脾肿大的症状，这是最常见的发现。无症状的 CML 患者很少见。我们报告了一例无脾肿大的无症状慢性期慢性髓性白血病 BCR-ABL（+）患者，该患者对伊马替尼有血液学和分子学反应。
