Cheema Tayyab, Balek Malek, Smith Patrick, Hanan Saad
Internal Medicine, West Suburban Medical Center, Chicago, USA.
Cardiology, West Suburban Medical Center, Chicago, USA.
Cureus. 2022 Feb 8;14(2):e22040. doi: 10.7759/cureus.22040. eCollection 2022 Feb.
Marfan syndrome is a rare autosomal dominant disorder of the connective tissue. It results in a mutation in the Fibrillin-1 protein gene. We present a case of Marfan's syndrome in a young adult with life-threatening, sudden onset of chest pain secondary to a non-ST elevation myocardial infarction (NSTEMI) in the setting of an aortic pseudoaneurysm. Taking into consideration potential life-threatening underlying processes, a thorough and detailed methodology must be undertaken when encountering chest pain in a Marfan's syndrome patient. This case highlights the importance of utilizing a multi-disciplinary approach to the complexities of Marfan syndrome.
马凡综合征是一种罕见的常染色体显性结缔组织疾病。它是由原纤蛋白-1蛋白基因发生突变所致。我们报告一例年轻成年马凡综合征患者，其在主动脉假性动脉瘤的情况下，因非ST段抬高型心肌梗死（NSTEMI）突然出现危及生命的胸痛。鉴于潜在的危及生命的基础疾病，在遇到马凡综合征患者胸痛时，必须采用全面而详细的方法。本病例突出了采用多学科方法应对马凡综合征复杂性的重要性。
