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Editorial: Plasticity of Endogenous Pain Modulatory Circuits in Neuropathy.

作者信息

Patel Ryan, Lumb Bridget M, Bannister Kirsty

机构信息

Wolfson Centre for Age Related Diseases, King's College London, London, United Kingdom.

School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, United Kingdom.

出版信息

Front Pain Res (Lausanne). 2021 Oct 21;2:776948. doi: 10.3389/fpain.2021.776948. eCollection 2021.

DOI:10.3389/fpain.2021.776948
PMID:35295507
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8915642/
Abstract
摘要

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本文引用的文献

1
Simultaneous brain, brainstem, and spinal cord pharmacological-fMRI reveals involvement of an endogenous opioid network in attentional analgesia.同时进行脑、脑干和脊髓的药理学 fMRI 研究揭示了内源性阿片网络在注意力镇痛中的作用。
Elife. 2022 Jan 26;11:e71877. doi: 10.7554/eLife.71877.
2
Systematic review with meta-analysis: conditioned pain modulation in patients with the irritable bowel syndrome.系统评价与荟萃分析：肠易激综合征患者的条件性疼痛调制。
Aliment Pharmacol Ther. 2018 Oct;48(8):797-806. doi: 10.1111/apt.14965. Epub 2018 Sep 11.
3
The plasticity of descending controls in pain: translational probing.疼痛中下行控制的可塑性：转化性探索。
J Physiol. 2017 Jul 1;595(13):4159-4166. doi: 10.1113/JP274165. Epub 2017 May 26.
4
A Brainstem-Spinal Cord Inhibitory Circuit for Mechanical Pain Modulation by GABA and Enkephalins.一个由γ-氨基丁酸（GABA）和脑啡肽介导的用于调节机械性疼痛的脑干-脊髓抑制性回路。
Neuron. 2017 Feb 22;93(4):822-839.e6. doi: 10.1016/j.neuron.2017.01.008. Epub 2017 Feb 2.
5
Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis.成人神经性疼痛的药物治疗：一项系统评价与荟萃分析。
Lancet Neurol. 2015 Feb;14(2):162-73. doi: 10.1016/S1474-4422(14)70251-0. Epub 2015 Jan 7.
6
Tapentadol potentiates descending pain inhibition in chronic pain patients with diabetic polyneuropathy.曲马多增强伴有糖尿病性多发性神经病的慢性疼痛患者的下行性疼痛抑制。
Br J Anaesth. 2014 Jul;113(1):148-56. doi: 10.1093/bja/aeu056. Epub 2014 Apr 8.
7
Facilitated temporal processing of pain and defective supraspinal control of pain in cluster headache.丛集性头痛中疼痛的时间处理得到促进，疼痛的脊髓上控制缺陷。
Pain. 2013 Aug;154(8):1325-32. doi: 10.1016/j.pain.2013.04.012. Epub 2013 Apr 9.
8
Endogenous analgesic action of the pontospinal noradrenergic system spatially restricts and temporally delays the progression of neuropathic pain following tibial nerve injury.内侧丘系下行性去甲肾上腺素能系统的内源性镇痛作用在空间上限制并在时间上延迟了胫神经损伤后神经病理性疼痛的进展。
Pain. 2013 Sep;154(9):1680-1690. doi: 10.1016/j.pain.2013.05.010. Epub 2013 May 14.
9
Transition to persistent orofacial pain after nerve injury involves supraspinal serotonin mechanisms.神经损伤后持续性或面部疼痛的转变涉及到中枢神经系统的血清素机制。
J Neurosci. 2013 Mar 20;33(12):5152-61. doi: 10.1523/JNEUROSCI.3390-12.2013.
10
Conditioned pain modulation predicts duloxetine efficacy in painful diabetic neuropathy.条件性疼痛调制可预测度洛西汀治疗糖尿病性神经痛的疗效。
Pain. 2012 Jun;153(6):1193-1198. doi: 10.1016/j.pain.2012.02.021. Epub 2012 Apr 3.