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MRI诊断小儿及青少年急性前交叉韧带撕裂合并半月板损伤的敏感性和特异性

Sensitivity and Specificity of MRI in Diagnosing Concomitant Meniscal Injuries With Pediatric and Adolescent Acute ACL Tears.

作者信息

Dawkins Brody J, Kolin David A, Park Joshua, Fabricant Peter D, Gilmore Allison, Seeley Mark, Mistovich R Justin

机构信息

SUNY Downstate Health Sciences University, Brooklyn, New York, USA.

Weill Cornell Graduate School of Medical Sciences, New York, New York, USA.

出版信息

Orthop J Sports Med. 2022 Mar 9;10(3):23259671221079338. doi: 10.1177/23259671221079338. eCollection 2022 Mar.

Abstract

BACKGROUND

Preoperative diagnosis of concomitant meniscal tears in pediatric and adolescent patients with acute anterior cruciate ligament (ACL) deficiency is challenging.

PURPOSE

To investigate the diagnostic performance of magnetic resonance imaging (MRI) in detecting meniscal injuries for pediatric and adolescent patients with acute ACL tears.

STUDY DESIGN

Cohort study (diagnosis); Level of evidence, 2.

METHODS

The authors retrospectively identified patients aged ≤18 years who underwent acute ACL reconstruction between 2006 and 2018 at 2 tertiary academic hospitals. The primary outcomes were arthroscopically confirmed medial, lateral, or any (defined as medial and/or lateral) meniscal tears. To control for chronically deficient knees, patients must have received their MRI study within 4 weeks of injury and must have undergone surgery no more than 8 weeks after their MRI study. Preoperative MRI reports were compared with the gold standard of arthroscopically confirmed tears to calculate sensitivity, specificity, positive predictive value, and negative predictive value. In a secondary analysis, patients were stratified by age into 2 groups (≤13 or ≥14 years), body mass index-for-age data from the Centers for Disease Control were used to classify patients as obese or nonobese, and differences between sensitivity and specificity proportions were analyzed using chi-square test for homogeneity.

RESULTS

Overall, 406 patients with a mean age of 15.4 years (range, 10-18 years) were identified. The sensitivity, specificity, positive predictive value, and negative predictive value were as follows: for lateral meniscal (LM) tears, 51.0%, 86.5%, 78.3%, and 65.0%; for medial meniscal tears, 83.2%, 80.6%, 62.3%, and 92.5%; and for any meniscal tear, 75.0%, 72.1%, 81.5%, and 63.8%, respectively. In the stratified analysis, MRI was less specific for the following diagnoses: any meniscal tear in patients aged ≤13 years ( = .048) and LM tears in obese patients ( = .020).

CONCLUSION

The diagnostic ability of MRI to predict meniscal injuries present at acute ACL reconstruction was moderate. Performance was poorest at the lateral meniscus, where MRI failed to detect 97 tears that were found arthroscopically. Specificity was significantly lower in younger patients for any meniscal tear and in obese patients for LM tears.

摘要

背景

对于患有急性前交叉韧带(ACL)损伤的儿童和青少年患者,术前诊断合并半月板撕裂具有挑战性。

目的

探讨磁共振成像(MRI)对急性ACL撕裂的儿童和青少年患者半月板损伤的诊断效能。

研究设计

队列研究(诊断);证据等级,2级。

方法

作者回顾性纳入了2006年至2018年期间在2家三级学术医院接受急性ACL重建手术的18岁及以下患者。主要结局为关节镜检查确诊的内侧、外侧或任何(定义为内侧和/或外侧)半月板撕裂。为了排除长期ACL功能不全的膝关节,患者必须在受伤后4周内接受MRI检查,且必须在MRI检查后不超过8周接受手术。将术前MRI报告与关节镜检查确诊撕裂的金标准进行比较,以计算敏感性、特异性、阳性预测值和阴性预测值。在二次分析中,将患者按年龄分为两组(≤13岁或≥14岁),使用疾病控制中心的年龄别体重指数数据将患者分为肥胖或非肥胖,并使用卡方检验进行同质性分析,以分析敏感性和特异性比例之间的差异。

结果

总体而言,共纳入406例患者,平均年龄15.4岁(范围10 - 18岁)。敏感性、特异性、阳性预测值和阴性预测值如下:外侧半月板(LM)撕裂分别为51.0%、86.5%、78.3%和65.0%;内侧半月板撕裂分别为83.2%、80.6%、62.3%和92.5%;任何半月板撕裂分别为75.0%、72.1%、81.5%和63.8%。分层分析显示,MRI对于以下诊断的特异性较低:≤13岁患者的任何半月板撕裂(P = 0.048)以及肥胖患者的LM撕裂(P = 0.020)。

结论

MRI预测急性ACL重建时存在的半月板损伤的诊断能力中等。在外侧半月板处表现最差,MRI未能检测到关节镜检查发现的97例撕裂。对于任何半月板撕裂,年轻患者的特异性显著较低;对于LM撕裂,肥胖患者的特异性显著较低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37d8/8918745/3308f890a7cc/10.1177_23259671221079338-fig1.jpg

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