Covid Internal Medicine Unit, Department of Translational Medical Sciences, AOU Federico II, University of Naples Federico II, Via S. Pansini, 5, 80131, Naples, Italy.
Covid Infectious Diseases Unit, Department of Clinical Medicine and Surgery, AOU Federico II, University of Naples Federico II, Naples, Italy.
Aging Clin Exp Res. 2022 Apr;34(4):939-944. doi: 10.1007/s40520-022-02101-3. Epub 2022 Mar 16.
The study assesses the reliability of fr-AGILE, a validated rapid tool used for the evaluation of multidimensional frailty in older adults hospitalized with COVID-19.
Two different staff members independently assessed the presence of frailty in 144 patients aged ≥ 65 years affected by COVID-19 using the fr-AGILE tool. The internal consistency of fr-AGILE was evaluated by examining the item-total correlations and the Kuder-Richardson (KR) formula. The inter-rater reliability was evaluated using linear weighted kappa.
Multidimensional frailty severity increases with age and is associated to higher use of non-invasive ventilation (p = 0.025), total severity score on chest tomography (p = 0.001) and in-hospital mortality (p = 0.032). Fr-AGILE showed good internal consistency (KR-20 = 0.742) and excellent inter-rater reliability (weighted kappa = 0.752 and 0.878 for frailty score and frailty degree, respectively).
fr-AGILE tool can quickly identify and quantify multidimensional frailty in hospital settings for older patient affected by COVID-19.
本研究评估了 fr-AGILE 的可靠性，fr-AGILE 是一种经过验证的快速工具，用于评估 COVID-19 住院老年患者的多维虚弱程度。
两名不同的工作人员使用 fr-AGILE 工具，对 144 名年龄≥65 岁的 COVID-19 患者的虚弱情况进行独立评估。通过检查项目总分相关性和 Kuder-Richardson（KR）公式，评估 fr-AGILE 的内部一致性。使用线性加权kappa 评估评分者间可靠性。
多维虚弱严重程度随年龄增长而增加，与更高的无创通气使用率（p=0.025）、胸部断层扫描总严重程度评分（p=0.001）和住院死亡率（p=0.032）相关。fr-AGILE 显示出良好的内部一致性（KR-20=0.742）和极好的评分者间可靠性（虚弱评分和虚弱程度的加权kappa 分别为 0.752 和 0.878）。
fr-AGILE 工具可在 COVID-19 老年住院患者中快速识别和量化多维虚弱。
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