Marhana Isnin Anang, Jiwangga Dhihintia
Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.
Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.
Int J Surg Case Rep. 2022 Apr;93:106928. doi: 10.1016/j.ijscr.2022.106928. Epub 2022 Mar 9.
Solitary fibrous tumor of pleura (SFTP) is a rare condition. Clinical symptoms and non-specific radiological features in both tumors make preoperative diagnosis difficult to establish.
A Javanese 47-year-old female complained of chest pain and shortness of breath which an X-ray and CT-Scan of the thorax showed giant cell metastases in the lung. Signs and symptoms indicate pulmonary sclerosing pneumocytoma (PSP) and the patient underwent thoracic surgery which was first performed with angiographic embolization. Furthermore, an anatomical pathology analysis was performed with suspected SFTP, supported by the IHC test, which found CD34 (+), EMA (-), and S100 (-). Thoracic surgery followed by radiotherapy and chemotherapy is recommended in SFTP patients.
The SFTP and PSP have non-specific clinical symptoms and radiological features. Anatomic pathology and IHC test are definitive diagnostic tools from SFTP and PSP. Establishing a preoperative diagnosis of SFTP and PSP is quite difficult. Surgical resection is the treatment of choice for both.
The comparison of SFTP and PSP can be seen results of the anatomical pathology analysis and IHC test.
胸膜孤立性纤维瘤（SFTP）是一种罕见疾病。两种肿瘤的临床症状和非特异性放射学特征使得术前诊断难以确立。
一名47岁的爪哇女性主诉胸痛和呼吸急促，胸部X线和CT扫描显示肺部有巨细胞转移。体征和症状提示为肺硬化性细胞瘤（PSP），该患者接受了胸外科手术，手术首先进行了血管造影栓塞。此外，对疑似SFTP进行了解剖病理学分析，并得到免疫组化检测的支持，结果发现CD34（+）、EMA（-）和S100（-）。对于SFTP患者，建议进行胸外科手术，随后进行放疗和化疗。
SFTP和PSP具有非特异性临床症状和放射学特征。解剖病理学和免疫组化检测是SFTP和PSP的确诊诊断工具。术前确立SFTP和PSP的诊断相当困难。手术切除是两者的首选治疗方法。
通过解剖病理学分析和免疫组化检测的结果可以对SFTP和PSP进行比较。
