Opt Express. 2022 Mar 14;30(6):9233-9255. doi: 10.1364/OE.432263.
In this research work, an anisotropic photonic crystal fiber (PCF) biosensor working on a refractive index (RI) variation and based on surface plasmon resonance (SPR) is presented. Liquid analytes (LA) having a RI within the range of 1.340 to 1.380 RIU are investigated from the proposed biosensor. Spectroscopy analysis of LA having RI values of 1.340 RIU, 1.360 RIU, and 1.380 RIU is performed from the developed sensing setup for modeling an ultrasensitive biosensor. The numerical analysis of the sensing parameters for the proposed sensor presents a maximum wavelength sensitivity (WS) of 20000 nm/RIU for x- polarization (x - pol.) and 18000 nm/RIU for y- polarization (y - pol.), respectively, using the wavelength interrogation technique. Maximum amplitude sensitivity (AS) of 2158 RIU and 3167 RIU is obtained for x - pol. and y - pol., respectively, using the amplitude interrogation technique. Maximum sensor resolution (SR) of 5.00 × 10RIU and 5.55 × 10RIU is obtained for x - pol. and y - pol., respectively. The linear relationship of the resonant wavelength (RW) with the RI produces R = 0.9972 and R = 0.9978, corresponding to a degree (2) for x - pol. and y - pol., respectively. The figure of merit (FOM) for x - pol. and y - pol. are 93.45 RIU and 105.88 RIU, respectively. The sensing parameters have obtained the maximum value for the LA having a RI value of 1.375 RIU.
在这项研究工作中，提出了一种基于折射率（RI）变化和表面等离子体共振（SPR）的各向异性光子晶体光纤（PCF）生物传感器。研究了RI 范围在 1.340 到 1.380 RIU 之间的液体分析物（LA）。从所开发的传感装置中对 RI 值为 1.340 RIU、1.360 RIU 和 1.380 RIU 的 LA 进行光谱分析，为超灵敏生物传感器建模。对所提出的传感器的传感参数进行数值分析，对于 x 偏振（x 偏振）和 y 偏振（y 偏振），分别得到最大波长灵敏度（WS）为 20000 nm/RIU 和 18000 nm/RIU，使用波长询问技术。使用幅度询问技术，对于 x 偏振和 y 偏振，分别得到最大幅度灵敏度（AS）为 2158 RIU 和 3167 RIU。对于 x 偏振和 y 偏振，分别得到最大传感器分辨率（SR）为 5.00×10RIU 和 5.55×10RIU。共振波长（RW）与 RI 的线性关系产生 R ＝0.9972 和 R ＝0.9978，分别对应于 x 偏振和 y 偏振的（2）度。x 偏振和 y 偏振的品质因数（FOM）分别为 93.45 RIU 和 105.88 RIU。对于 RI 值为 1.375 RIU 的 LA，传感参数获得了最大值。
