Lui P, Ng H S, Teh L B, Kwok K C, Ong Y Y, Tan L, Low C H, Rauff A, Seah C S
Ann Acad Med Singap. 1986 Apr;15(2):182-5.
Fifty consecutive patients (32 males and 18 females) with cholestatic jaundice were examined by grey-scale ultrasound from June 1981 to June 1983. All patients were studied without access to case notes. All patients had a diagnosis established by subsequent liver biopsy, clinical course, surgery or autopsy. Using the presence or absence of a dilated biliary system as the criterion, intrahepatic or extrahepatic cholestasis was correctly differentiated in 48 of the 50 patients, giving an overall accuracy of 96%. All 16 patients with intrahepatic cholestasis were correctly identified. Two of the 34 patients with extrahepatic cholestasis, each of whom had biliary stones, were misdiagnosed as intrahepatic cholestasis. In the 34 patients with extra-hepatic cholestasis, site of obstruction was defined in 55.9%, and specific aetiology diagnosed in 44.1%. Ultrasound proves to be an accurate method for the evaluation of cholestatic jaundice, and would have a definite value as a screening test before proceeding to invasive studies.
1981年6月至1983年6月期间，对50例连续性胆汁淤积性黄疸患者（32例男性，18例女性）进行了灰阶超声检查。所有患者均在未查阅病历的情况下接受研究。所有患者均通过后续的肝活检、临床病程、手术或尸检确定诊断。以有无扩张的胆道系统为标准，50例患者中有48例正确区分了肝内或肝外胆汁淤积，总体准确率为96%。16例肝内胆汁淤积患者全部被正确识别。34例肝外胆汁淤积患者中有2例（均有胆结石）被误诊为肝内胆汁淤积。在34例肝外胆汁淤积患者中，55.9%明确了梗阻部位，44.1%诊断出了具体病因。超声被证明是评估胆汁淤积性黄疸的一种准确方法，在进行侵入性检查之前作为筛查试验具有一定价值。
