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儿童口腔黏膜炎的管理。

Management of oral mucositis in children.

机构信息

Oral & Maxillofacial Surgery and Diagnostic Sciences Department, College of Dentistry, Najran University, Najran, Saudi Arabia.

出版信息

Eur Rev Med Pharmacol Sci. 2022 Mar;26(5):1648-1657. doi: 10.26355/eurrev_202203_28233.

DOI:10.26355/eurrev_202203_28233
PMID:35302212
Abstract

OBJECTIVE

Children undergoing chemotherapy or hematopoietic stem cell transplantation may suffer from Oral mucositis. Therefore, the aim of this systematic review was to find the protocols which are used in the management of oral mucositis (OM) in children.

MATERIALS AND METHODS

A search was performed to find the related studies. After reading the searched articles, 15 studies were selected for this review.

RESULTS

Good oral care, glutamine, some biological agents, and laser therapy, had a significant effect to reduce the pain sensation and occurrence of oral mucositis in children.

CONCLUSIONS

It has been concluded that there are many types of management, such as oral care and laser therapy, which can be used to reduce the severity of oral mucositis.

摘要

目的

接受化疗或造血干细胞移植的儿童可能会患有口腔黏膜炎。因此,本系统评价的目的是找到用于儿童口腔黏膜炎(OM)管理的方案。

材料与方法

进行了搜索以查找相关研究。在阅读了搜索到的文章后,选择了 15 项研究进行综述。

结果

良好的口腔护理、谷氨酰胺、一些生物制剂和激光治疗对减轻儿童口腔黏膜炎的疼痛和发生有显著效果。

结论

结论是有许多种管理方法,如口腔护理和激光治疗,可以用来减轻口腔黏膜炎的严重程度。

相似文献

1
Management of oral mucositis in children.儿童口腔黏膜炎的管理。
Eur Rev Med Pharmacol Sci. 2022 Mar;26(5):1648-1657. doi: 10.26355/eurrev_202203_28233.
2
Oral mucositis in pediatric patients undergoing hematopoietic stem cell transplantation: clinical outcomes in a context of specialized oral care using low-level laser therapy.接受造血干细胞移植的儿科患者的口腔黏膜炎:在使用低强度激光疗法进行专业口腔护理背景下的临床结果
Pediatr Transplant. 2015 May;19(3):316-25. doi: 10.1111/petr.12440. Epub 2015 Feb 13.
3
Systematic review of photobiomodulation for the management of oral mucositis in cancer patients and clinical practice guidelines.系统评价光生物调节治疗癌症患者口腔黏膜炎的疗效和临床实践指南
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Eur J Pediatr. 2018 Jan;177(1):7-17. doi: 10.1007/s00431-017-3043-4. Epub 2017 Nov 11.
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Preliminary study in a new protocol for the treatment of oral mucositis in pediatric patients undergoing hematopoietic stem cell transplantation (HSCT) and chemotherapy (CT).一项针对接受造血干细胞移植(HSCT)和化疗(CT)的儿科患者口腔黏膜炎治疗新方案的初步研究。
Lasers Med Sci. 2017 Aug;32(6):1423-1428. doi: 10.1007/s10103-017-2266-y. Epub 2017 Jun 29.
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Low-Level Laser Therapy for the Treatment of Oral Mucositis Induced by Hematopoietic Stem Cell Transplantation: A Systematic Review with Meta-Analysis.低水平激光疗法治疗造血干细胞移植后口腔黏膜炎的系统评价与荟萃分析。
Medicina (Kaunas). 2023 Aug 3;59(8):1413. doi: 10.3390/medicina59081413.
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Severity of oral mucositis in patients undergoing hematopoietic cell transplantation and an oral laser phototherapy protocol: a survey of 30 patients.造血细胞移植患者口腔黏膜炎的严重程度及口腔激光光疗方案:30例患者的调查
Photomed Laser Surg. 2009 Feb;27(1):137-44. doi: 10.1089/pho.2007.2225.
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Evaluating high power laser therapy (HPLT) as treatment for chemotherapy-induced oral mucositis in paediatric patients with oncohematological diseases.评估高功率激光疗法(HPLT)作为患有血液肿瘤疾病的儿科患者化疗引起的口腔黏膜炎的治疗方法。
Int J Paediatr Dent. 2023 May;33(3):269-277. doi: 10.1111/ipd.13050. Epub 2023 Mar 10.
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Low-level laser therapy prevents severe oral mucositis in patients submitted to hematopoietic stem cell transplantation: a randomized clinical trial.低强度激光治疗可预防接受造血干细胞移植患者的严重口腔黏膜炎:一项随机临床试验。
Support Care Cancer. 2016 Mar;24(3):1035-42. doi: 10.1007/s00520-015-2881-8. Epub 2015 Aug 7.
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Effect of prophylactic low level laser therapy on oral mucositis: a systematic review and meta-analysis.预防性低强度激光治疗对口腔黏膜炎的影响:一项系统评价与荟萃分析。
PLoS One. 2014 Sep 8;9(9):e107418. doi: 10.1371/journal.pone.0107418. eCollection 2014.

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J Clin Med. 2025 Aug 20;14(16):5869. doi: 10.3390/jcm14165869.
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Knowledge, attitudes, and practices of family members of children undergoing chemoradiotherapy regarding oral mucositis.接受放化疗儿童的家庭成员关于口腔黏膜炎的知识、态度和行为
Asia Pac J Oncol Nurs. 2025 May 15;12:100724. doi: 10.1016/j.apjon.2025.100724. eCollection 2025 Dec.
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Photobiomodulation for Chemotherapy-Induced Oral Mucositis in Pediatric Patients.
光生物调节治疗儿科患者化疗诱导性口腔黏膜炎。
Biomolecules. 2023 Feb 23;13(3):418. doi: 10.3390/biom13030418.