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脑室内出血的发病率和严重程度:1981 - 1984年

Incidence and severity of intraventricular hemorrhage: 1981-1984.

作者信息

Batton D G, DeWitte D B, Boal D K, Nardis E E, Maisels M J

出版信息

Am J Perinatol. 1986 Oct;3(4):353-6. doi: 10.1055/s-2007-999896.

Abstract

We have examined the trend in the incidence and mortality of intraventricular hemorrhage (IVH) in low birthweight infants from 1981 through 1984. During this time we admitted 407 infants in the first week of life with a birthweight less than or equal to 1500 gm in whom a cranial ultrasonogram or autopsy had been performed. Though the mean birthweight and gestational age, proportion of infants who were inborn, and percentage of infants requiring mechanical ventilation did not change over the 4 years, cesarean deliveries were performed more frequently (P less than .001). The overall incidence of IVH was 62% in 1981, 56% in 1982, 49% in 1983, and 58% in 1984, thus no significant trend was evident. Although the incidence of minor hemorrhages (grades I and II) remained relatively constant, there was a decrease in the incidence of grade III IVH (1981, 11%; 1984, 2%, P = .01). The incidence of grade IV hemorrhage did not change during the 4 years and ranged from 7 to 9%. Mortality rate for all infants weighing less than or equal to 1500 gm and for infants with a minor hemorrhage remained unchanged; however, the mortality rate for infants with a major hemorrhage (grade III or IV) tended to decrease (P = .07). We conclude that although some minor changes in the incidence and mortality have occurred, IVH continues to be a major problem in very-low-birthweight infants at our institution.

摘要

我们研究了1981年至1984年低出生体重儿脑室内出血(IVH)的发病率和死亡率趋势。在此期间,我们收治了407例出生体重小于或等于1500克且在出生第一周内接受了头颅超声检查或尸检的婴儿。尽管这4年间婴儿的平均出生体重、胎龄、足月儿比例以及需要机械通气的婴儿百分比没有变化,但剖宫产的实施频率更高(P<0.001)。1981年IVH的总体发病率为62%,1982年为56%,1983年为49%,1984年为58%,因此没有明显的显著趋势。虽然轻度出血(I级和II级)的发病率相对保持稳定,但III级IVH的发病率有所下降(1981年为11%;1984年为2%,P=0.01)。IV级出血的发病率在这4年中没有变化,范围在7%至9%之间。所有体重小于或等于1500克的婴儿以及轻度出血婴儿的死亡率保持不变;然而,重度出血(III级或IV级)婴儿的死亡率有下降趋势(P=0.07)。我们得出结论,尽管发病率和死亡率发生了一些微小变化,但在我们机构中,IVH仍然是极低出生体重儿的一个主要问题。

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