Department of Orthopaedic Surgery, Atrium Health, Charlotte, NC.
OrthoCarolina, OrthoCarolina Hand Center, Charlotte, NC.
J Hand Surg Am. 2023 Jul;48(7):735.e1-735.e7. doi: 10.1016/j.jhsa.2022.01.018. Epub 2022 Mar 15.
The purpose of this study was to review a series of cases in which the induced membrane technique was used for fractures with segmental bone loss in the upper extremity. We aimed to examine patient indications, outcomes based on union rates, and complications associated with this technique.
An institutional review board-approved database at our institution was used to identify patients based on either diagnosis or procedure codes commonly used during the induced membrane treatment. The database was queried between 2003 and 2020 and included patients with segmental bone defects from acute trauma, nonunions, and infections. Demographic data, mechanism of injury, size and extent of the bone defect, treatment indication and methods along with intraoperative and postoperative complications were retrospectively reviewed.
We identified 23 patients who met our inclusion criteria, including 15 patients with traumatic segmental bone loss and 8 patients with chronic nonunions and/or infections. Fourteen cases involving the bones of the forearm, 8 cases involving the metacarpals and 3 cases involving the phalanges were identified. Radiographic union was ultimately demonstrated in 21/23 patients (91.3%) with a median time to union of 20 weeks (range 13-29 weeks). A total of 10 patients required unplanned reoperation, with 4 nonunions requiring repeat plating and grafting procedures, and 1 patient ultimately underwent amputation for persistent infection.
The induced membrane technique represents an effective treatment option for acute traumatic bone loss as well as chronic fracture nonunions. The technique has potential challenges, as 10 patients (43.5%) in our series required unplanned reoperations with 4 patients (17.4%) requiring a repeat intervention for persistent nonunion.
TYPE OF STUDY/LEVEL OF EVIDENCE: Therapeutic IV.
本研究旨在回顾一系列采用诱导膜技术治疗上肢节段性骨缺损骨折的病例。我们旨在检查患者的适应证、基于愈合率的结果以及与该技术相关的并发症。
我们使用机构审查委员会批准的我院数据库,根据诊断或手术代码识别患者,这些代码通常用于诱导膜治疗。该数据库在 2003 年至 2020 年间进行了查询,包括急性创伤、骨不连和感染导致的节段性骨缺损患者。回顾性分析了患者的人口统计学数据、损伤机制、骨缺损的大小和范围、治疗指征和方法以及术中及术后并发症。
我们确定了符合纳入标准的 23 名患者,其中 15 名患者为创伤性节段性骨缺损,8 名患者为慢性骨不连和/或感染。涉及前臂骨的病例有 14 例,涉及掌骨的病例有 8 例,涉及指骨的病例有 3 例。最终有 21/23 例(91.3%)患者影像学上愈合,愈合的中位数时间为 20 周(范围 13-29 周)。共有 10 名患者需要非计划再次手术,其中 4 例骨不连需要再次行钢板和植骨手术,1 例患者因持续性感染最终行截肢。
诱导膜技术是治疗急性创伤性骨丢失和慢性骨折不连的有效治疗选择。该技术存在潜在的挑战,因为我们的系列中有 10 名患者(43.5%)需要非计划再次手术,其中 4 名患者(17.4%)因持续性骨不连需要再次干预。
研究类型/证据水平:治疗性 IV 级。