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胰岛素瘤:一种不常见的谵妄病因。

Insulinoma: an uncommon cause of delirium.

机构信息

Lagan Valley Hospital, South Eastern Health and Social Care Trust, Lisburn BT28 1JP, UK.

出版信息

Age Ageing. 2022 Mar 1;51(3). doi: 10.1093/ageing/afac055.

DOI:10.1093/ageing/afac055
PMID:35305086
Abstract

We present the case of an 83-year-old woman with recurrent episodes of delirium occurring overnight, associated with hypoglycaemia. Other causes for delirium were excluded. Laboratory findings were in keeping with endogenous insulin production. Computerised tomography imaging revealed a small mass in the pancreas supporting a presumed diagnosis of an insulinoma. Given the patient's frailty and cognitive impairment, a conservative management approach was taken. Diazoxide was commenced with resolution of episodes of delirium. This case highlights hypoglycaemia, and insulinoma, as a rare, but treatable cause of delirium. It demonstrates the importance of blood sugar screening in delirium. It emphasises the holistic modifications to management, which must be taken to ensure patient-centred care when caring for an older adult living with frailty, who may have cognitive impairment.

摘要

我们报告了一例 83 岁老年女性患者,其反复发作的谵妄症状仅在夜间出现,同时伴有低血糖。已排除其他导致谵妄的原因。实验室检查结果符合内源性胰岛素分泌。计算机断层扫描成像显示胰腺内有一小肿块,支持胰岛素瘤的诊断。鉴于患者身体虚弱和认知障碍,我们采取了保守治疗方法。开始使用二氮嗪治疗后,谵妄发作得到缓解。本病例强调了低血糖和胰岛素瘤是导致谵妄的罕见但可治疗的原因。它还说明了在谵妄患者中进行血糖筛查的重要性。它强调了在照顾患有衰弱和认知障碍的老年患者时,必须进行全面的管理调整,以确保以患者为中心的护理。

相似文献

1
Insulinoma: an uncommon cause of delirium.胰岛素瘤:一种不常见的谵妄病因。
Age Ageing. 2022 Mar 1;51(3). doi: 10.1093/ageing/afac055.
2
[Severe hypoglycaemia due to insulinoma after gastric bypass surgery].[胃旁路手术后因胰岛素瘤导致的严重低血糖症]
Ugeskr Laeger. 2018 Apr 23;180(17).
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Lesson of the month: Recurrent falls and hypoglycaemia in an older woman.本月课程:老年女性反复跌倒和低血糖。
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Insulinoma induced hypoglycaemia in a Jamaican patient.一名牙买加患者因胰岛素瘤引发低血糖症。
West Indian Med J. 2007 Mar;56(2):182-6. doi: 10.1590/s0043-31442007000200015.
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Insulinoma presenting as postprandial hypoglycaemia.胰岛素瘤表现为餐后低血糖。
BMJ Case Rep. 2011 Aug 24;2011:bcr0720114477. doi: 10.1136/bcr.07.2011.4477.
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Insulinoma as a cause of seizure-like activity and spontaneous hypoglycaemia.胰岛素瘤作为癫痫样活动和自发性低血糖的病因。
BMJ Case Rep. 2023 Jan 10;16(1):e250799. doi: 10.1136/bcr-2022-250799.
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[A rare cause of hypoglycaemia in a patient with type 2 diabetes].[2型糖尿病患者低血糖的罕见病因]
Dtsch Med Wochenschr. 2009;134 Suppl Falldatenbank:F2. doi: 10.1055/s-0028-1082826. Epub 2009 Feb 23.
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A rare case of insulinoma presenting with postprandial hypoglycemia.一例罕见的胰岛素瘤伴餐后低血糖病例。
Am J Case Rep. 2014 Nov 9;15:488-91. doi: 10.12659/AJCR.891336.
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Insulinoma: important in the differential diagnosis of persistent hypoglycaemia unrelated to diabetes.胰岛素瘤:在与糖尿病无关的持续性低血糖鉴别诊断中具有重要意义。
Med J Aust. 2018 Mar 5;208(4):157-158. doi: 10.5694/mja17.00174.
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A rare cause of hypoglycemia in a type 2 diabetic patient: insulinoma.2 型糖尿病患者低血糖的罕见病因:胰岛素瘤。
J Diabetes Complications. 2012 Jan-Feb;26(1):65-7. doi: 10.1016/j.jdiacomp.2011.12.003. Epub 2012 Mar 6.

引用本文的文献

1
The Occult Insulinoma Was Localized Using Endoscopic Ultrasound Guidance: A Case Report.经内镜超声引导定位隐匿性胰岛素瘤:一例报告
Clin Case Rep. 2025 Feb 10;13(2):e9634. doi: 10.1002/ccr3.9634. eCollection 2025 Feb.
2
Endogenous hyperinsulinemic hypoglycemia: case series and literature review.内源性高胰岛素血症性低血糖症:病例系列和文献复习。
Endocrine. 2023 Apr;80(1):40-46. doi: 10.1007/s12020-022-03268-5. Epub 2022 Dec 2.