Liu Yanjun, Liu Yi, Li Panpan, Li Ziwei
State Key Laboratory of Food Science and Technology, School of Food Science and Technology, National Engineering Research Center for Functional Food, National Engineering Laboratory for Cereal Fermentation Technology, Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province, Jiangnan University, 1800 Lihu Road, Wuxi 214122, Jiangsu, China.
West China School of Public Health/West China Fourth Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
Food Chem. 2022 Aug 15;385:132715. doi: 10.1016/j.foodchem.2022.132715. Epub 2022 Mar 15.
The objective of this study was to investigate the antibacterial activity and potential mechanism of cyclolinopeptides, a type of cyclic hydrophobic peptides present in flaxseed oil. In this study, 1-Mso cyclolinopeptides B and 1-Mso, 3-Mso-cyclolinopeptides F from flaxseed oil exhibited excellent antibacterial activity against Listeria monocytogenes through destroying bacterial cell membrane. Our results indicated that cyclolinopeptides are one of the antibacterial components in flaxseed oil. Also, the application of cyclolinopeptides B and 1-Mso, 3-Mso-cyclolinopeptides F in inhibiting the microbial contamination of beef was investigated as well. Thus, our study highlights the promising potential of cyclolinopeptides to serve as food additives or food preservations due to their strong antibacterial activity against Listeria monocytogenes.
本研究的目的是探究环亚麻肽（一种存在于亚麻籽油中的环状疏水肽）的抗菌活性及潜在机制。在本研究中，亚麻籽油中的1-Mso环亚麻肽B和1-Mso、3-Mso-环亚麻肽F通过破坏细菌细胞膜，对单核细胞增生李斯特菌表现出优异的抗菌活性。我们的结果表明，环亚麻肽是亚麻籽油中的抗菌成分之一。此外，还研究了环亚麻肽B和1-Mso、3-Mso-环亚麻肽F在抑制牛肉微生物污染方面的应用。因此，我们的研究突出了环亚麻肽作为食品添加剂或食品防腐剂的潜在前景，因为它们对单核细胞增生李斯特菌具有强大的抗菌活性。
