Julius Global Health, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands; Department of Epidemiology and Biostatistics, School of Public Health, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Public Health Nurses' School, Korle Bu, Accra, Ghana.
Prim Care Diabetes. 2022 Jun;16(3):341-349. doi: 10.1016/j.pcd.2022.01.011. Epub 2022 Mar 16.
Diabetes related amputations remain a major global problem, with devastating complications. We critically appraised relevant literature to quantify the prevalence of diabetes related amputations in sub-Saharan Africa (SSA). An electronic search was performed using the EMBASE and PubMed databases until 2020. Twenty-four out of 834 studies retrieved were included. The pooled prevalence of diabetic-related amputations was 36.9% (95%CI: 32.9%-40.8%). Complications of diabetes related amputations included infection, anaemia, foot deformity and mortality. The study revealed a substantial contribution of diabetes to the burden of amputations in SSA and suggests the need for further studies to assess how to reduce the incidence of diabetes, reduce the incidence of and or delay the progression of macro and microvascular complications of diabetes in SSA.
糖尿病相关截肢仍然是一个全球性的主要问题，会带来严重的并发症。我们对相关文献进行了批判性评估，以量化撒哈拉以南非洲（SSA）糖尿病相关截肢的患病率。使用 EMBASE 和 PubMed 数据库进行了电子搜索，截至 2020 年。从 834 项研究中检索到的 24 项研究被纳入。糖尿病相关截肢的总患病率为 36.9%（95%CI：32.9%-40.8%）。糖尿病相关截肢的并发症包括感染、贫血、足部畸形和死亡。研究表明，糖尿病在 SSA 截肢负担中占很大比例，这表明需要进一步研究如何降低糖尿病的发病率，减少 SSA 中糖尿病大血管和微血管并发症的发生率和/或延迟其进展。
