Department of Neurosurgery, New York Presbyterian Hospital, New York, New York.
Department of Pathology, New York Presbyterian Hospital, New York, New York.
World Neurosurg. 2022 Jun;162:15-16. doi: 10.1016/j.wneu.2022.03.046. Epub 2022 Mar 17.
An otherwise healthy 57-year-old man presented with intermittent low back pain and was incidentally found to have a left-sided paraspinal mass invading the spinal canal and causing spinal cord compression. He underwent a T11-12 hemilaminectomy, facetectomy, and instrumented fusion for a gross total resection with a good clinical outcome. Pathology revealed the lesion to be a ganglioneuroma. Ganglioneuroma is a rare and interesting pathology. These tumors are benign peripheral neuroblastic tumors derived from the neural crest and found along the entire neuroaxis. Tumors come to clinical attention if they cause symptomatic compression of neural structures or are found incidentally on imaging. Additionally, as these tumors share a common lineage with pheochromocytomas, systemic symptoms can be observed resulting from secretion of vasoactive peptides. The pathologic diagnosis of ganglioneuroma is predominantly based on morphology.
一位 57 岁的健康男性出现间歇性腰痛，偶然发现左侧脊柱旁肿块侵犯椎管并导致脊髓受压。他接受了 T11-12 半椎板切除术、关节突切除术和器械融合术，进行了大体全切除，临床结果良好。病理显示病变为神经节细胞瘤。神经节细胞瘤是一种罕见而有趣的病理学。这些肿瘤是源自神经嵴的良性外周神经母细胞瘤，沿整个神经轴发现。如果这些肿瘤引起神经结构的症状性压迫或在影像学上偶然发现，它们就会引起临床关注。此外，由于这些肿瘤与嗜铬细胞瘤具有共同的谱系，可能会观察到由于血管活性肽分泌而引起的全身症状。神经节细胞瘤的病理诊断主要基于形态学。
