Laboratoire Microbiologie Santé et Environnement, Doctoral School of Sciences and Technology, Faculty of Public Health, Lebanese University, Tripoli, Lebanon; Aix-Marseille University, IRD, APHM, MEPI, IHU Méditerranée infection, Faculté de Médecine et de Pharmacie, Marseille, France.
Laboratoire Microbiologie Santé et Environnement, Doctoral School of Sciences and Technology, Faculty of Public Health, Lebanese University, Tripoli, Lebanon.
Diagn Microbiol Infect Dis. 2022 May;103(1):115660. doi: 10.1016/j.diagmicrobio.2022.115660. Epub 2022 Feb 23.
Third generation cephalosporins (3GC)-resistant Neisseria flavescens could cause difficult-to-treat infections. This study aimed to investigate the genetic determinants of 3GC resistance using whole genome sequence comparisons of three N. flavescens; one of which was 3GC-resistant, while two were susceptible. Mutations in penA, ponA, and porB might be associated with the 3GC-resistance.
三代头孢菌素（3GC）耐药的黄色奈瑟菌可能引起难以治疗的感染。本研究旨在通过对三种黄色奈瑟菌的全基因组序列比较，来研究 3GC 耐药的遗传决定因素；其中一种对 3GC 耐药，而两种对 3GC 敏感。penA、ponA 和 porB 中的突变可能与 3GC 耐药有关。
