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青少年 1 型糖尿病:维生素 D 状况的影响。

DIABETES MELLITUS TYPE 1 IN ADOLESCENTS: IMPACT OF VITAMIN D STATUS.

机构信息

NATIONAL PIROGOV MEMORIAL MEDICAL UNIVERSITY, VINNYTSIA, UKRAINE.

出版信息

Wiad Lek. 2022;75(2):387-392.

Abstract

OBJECTIVE

The aim: To evaluate the effect of vitamin D deficiency or insufficiency on the compensation of the disease in adolescents with diabetes mellitus type 1.

PATIENTS AND METHODS

Materials and methods: 124 patients were examined, among them: 33 from the control group, 91 adolescents with type 1 diabetes mellitus. All patients were between 10-18 years old and were residents of the Podillya region of Ukraine.

RESULTS

Results: According to the results of the study Vitamin D levels in adolescents with type 1 diabetes mellitus are significantly lower, comparing with healthy adolescents of the same age group. Vitamin D levels among boys with type 1 diabetes mellitus were significantly lower comparing to girls of the same group. The boys of the control group had significantly higher levels of vitamin D in the blood comparing to boys with type 1 diabetes mellitus, p <0.001.

CONCLUSION

Conclusions: The majority of adolescents aged 13-18 years with type 1 diabetes mellitus have vitamin D deficiency or insufficiency regardless of the state of glycemic control of the disease.

摘要

目的

评估维生素 D 缺乏或不足对 1 型糖尿病青少年疾病代偿的影响。

患者和方法

共检查了 124 名患者,其中包括 33 名对照组和 91 名 1 型糖尿病青少年。所有患者年龄在 10-18 岁之间,均为乌克兰波迪利亚地区的居民。

结果

研究结果显示,1 型糖尿病青少年的维生素 D 水平明显低于同年龄组的健康青少年。1 型糖尿病男孩的维生素 D 水平明显低于同组女孩。与 1 型糖尿病男孩相比,对照组男孩的血液中维生素 D 水平明显更高,p<0.001。

结论

大多数 13-18 岁的 1 型糖尿病青少年无论疾病血糖控制状态如何,都存在维生素 D 缺乏或不足。

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