Chen Amanda Xy, Derrick Emily B, Beavis Paul A, House Imran G
Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia.
Immunol Cell Biol. 2022 May;100(5):304-307. doi: 10.1111/imcb.12545. Epub 2022 Apr 16.
In a recently published article, Melenhorst et al. performed a longitudinal analysis on chimeric antigen receptor (CAR) T cells isolated from patients over 10 years after therapy, revealing expansion of a long-lived CD4 CAR T-cell population with a cytotoxic phenotype.
在最近发表的一篇文章中，梅伦霍斯特等人对治疗后10多年从患者体内分离出的嵌合抗原受体（CAR）T细胞进行了纵向分析，发现具有细胞毒性表型的长寿CD4 CAR T细胞群体出现扩增。
