Wozniak J T, Orchard T L, Mackie P H, Mistry D K, Stuart J
J Clin Pathol. 1978 Jul;31(7):648-53. doi: 10.1136/jcp.31.7.648.
Patients with bacterial infection may show altered membrane permeability of the primary azurophilic lysosomes of blood neutrophils. A new enzyme cytochemical technique, sensitive to increased membrane permeability caused by contact of neutrophils with acetone, saponin, low pH, Streptolysin O, bacteria, and nylon wool, has been developed. The method is of potential value as a screening test for bacterial infection and for detecting neutrophil damage during filtration leucopheresis.
细菌感染患者血液中性粒细胞的初级嗜天青溶酶体膜通透性可能会发生改变。已开发出一种新的酶细胞化学技术,该技术对中性粒细胞与丙酮、皂角苷、低pH值、链球菌溶血素O、细菌及尼龙毛接触所引起的膜通透性增加敏感。该方法作为细菌感染的筛查试验以及检测白细胞去除术中中性粒细胞损伤具有潜在价值。