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惠比特犬导致维生素B12缺乏症。

Whippets Causing Vitamin B12 Deficiency.

作者信息

Maheshwari Mani, Athiraman Hemanthkumar

机构信息

Hospital Medicine, Banner Health, Mesa, USA.

Hospital Medicine, Banner Health, Phoenix, USA.

出版信息

Cureus. 2022 Mar 14;14(3):e23148. doi: 10.7759/cureus.23148. eCollection 2022 Mar.

DOI:10.7759/cureus.23148
PMID:35308182
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8923246/
Abstract

On the rise due to its effects of euphoria, recreational use of nitrous oxide can cause severe neurologic symptoms caused by marked and rapid onset of vitamin B12 deficiency. This is a case of a young 34-year-old male who presented with an inability to walk and confusion caused by vitamin B12 deficiency in the setting of recreational nitrous oxide use.

摘要

由于其欣快作用，氧化亚氮的娱乐性使用呈上升趋势，这可能会因维生素B12缺乏的显著且快速发作而导致严重的神经症状。本文报告一例34岁年轻男性病例，该患者在娱乐性使用氧化亚氮的情况下，因维生素B12缺乏出现行走困难和意识模糊。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96fe/8923246/31002c044578/cureus-0014-00000023148-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96fe/8923246/db9d48f50c4a/cureus-0014-00000023148-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96fe/8923246/31002c044578/cureus-0014-00000023148-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96fe/8923246/db9d48f50c4a/cureus-0014-00000023148-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96fe/8923246/31002c044578/cureus-0014-00000023148-i02.jpg

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引用本文的文献

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Nitrous Oxide Causing Subacute Combined Degeneration: A Case Report.一氧化二氮导致亚急性联合变性：一例报告
Cureus. 2024 Nov 30;16(11):e74871. doi: 10.7759/cureus.74871. eCollection 2024 Nov.
2
Nitrous Oxide Inhalant Abuse: Preliminary Results from a Cross-Sectional Study on Knowledge, Attitudes, and Practices of Italian Physicians (2023).笑气吸入滥用：一项关于意大利医生知识、态度和实践的横断面研究的初步结果（2023 年）。
Medicina (Kaunas). 2023 Oct 12;59(10):1820. doi: 10.3390/medicina59101820.
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Vitamin B deficiency presenting with a pancytopenia in pregnancy.

本文引用的文献

1
Nitrous oxide causes peripheral neuropathy in a dose dependent manner among recreational users.一氧化二氮在娱乐性使用者中以剂量依赖的方式引起周围神经病。
J Psychopharmacol. 2020 Feb;34(2):229-236. doi: 10.1177/0269881119882532. Epub 2019 Nov 4.
2
Vitamin B , folate, and the methionine remethylation cycle-biochemistry, pathways, and regulation.维生素 B 、叶酸和蛋氨酸再甲基化循环——生化、途径和调控。
J Inherit Metab Dis. 2019 Jul;42(4):673-685. doi: 10.1002/jimd.12009. Epub 2019 Jan 28.
3
No Laughing Matter: Presence, Consumption Trends, Drug Awareness, and Perceptions of "Hippy Crack" (Nitrous Oxide) among Young Adults in England.
孕期出现全血细胞减少的维生素B缺乏症。
BMJ Case Rep. 2023 Jan 12;16(1):e249955. doi: 10.1136/bcr-2022-249955.
4
Nitrous Oxide/Whippits-Induced Thoracic Spinal Cord Myelopathy and Cognitive Decline With Normal Serum Vitamin B₁₂.一氧化二氮/笑气所致胸椎脊髓病及认知功能减退伴血清维生素B₁₂正常
Cureus. 2022 Apr 29;14(4):e24581. doi: 10.7759/cureus.24581. eCollection 2022 Apr.
绝非儿戏：英国年轻人中“嬉皮士可卡因”（一氧化二氮）的存在、消费趋势、药物认知及看法
Front Psychiatry. 2018 Jan 22;8:312. doi: 10.3389/fpsyt.2017.00312. eCollection 2017.
4
Neurologic, psychiatric, and other medical manifestations of nitrous oxide abuse: A systematic review of the case literature.一氧化二氮滥用的神经、精神及其他医学表现：病例文献的系统评价
Am J Addict. 2016 Aug;25(5):358-69. doi: 10.1111/ajad.12372. Epub 2016 Apr 1.
5
The effects of nitrous oxide on vitamin B12 and homocysteine levels in methyltetrahydrofolate reductase gene mutation.氧化亚氮对甲基四氢叶酸还原酶基因突变中维生素B12和同型半胱氨酸水平的影响。
Bratisl Lek Listy. 2013;114(6):317-22. doi: 10.4149/bll_2013_067.
6
Drugs and vitamin B12 and folate metabolism.药物与维生素B12及叶酸代谢
Curr Concepts Nutr. 1983;12:73-87.