Aslam Hira, Khan Ali N, Chaudhary Ahmed Jamal, Iqbal Sana, Ismail Rana
Internal Medicine, Detroit Medical Center/Wayne State University (DMC/WSU) Sinai Grace Hospital, Detroit, USA.
Cureus. 2022 Feb 11;14(2):e22117. doi: 10.7759/cureus.22117. eCollection 2022 Feb.
Iron deficiency anemia is the leading cause of anemia all over the world. Iron deficiency is known to cause reactive thrombocytosis. However, arterial thrombosis secondary to reactive thrombocytosis is a rare entity. In this article, we present a case of a 37-year-old female with recurrent arterial thrombosis due to severe thrombocytosis caused by iron deficiency anemia. The patient developed spleen and kidney infractions, as well as abdominal aortic thrombosis. She was subsequently treated with iron and aspirin with an improvement of the anemia and thrombocytosis, with no further thrombotic complications. Arterial thrombosis is a very serious condition as the thrombus can embolize to carotid arteries leading to stroke or to peripheral blood vessels causing peripheral ischemia and gangrene. Iron deficiency anemia is a reversible cause of thrombocytosis that can be treated very easily to avoid thrombotic complications.
缺铁性贫血是全球贫血的主要原因。已知缺铁会导致反应性血小板增多症。然而,继发于反应性血小板增多症的动脉血栓形成是一种罕见的情况。在本文中,我们报告了一例37岁女性因缺铁性贫血导致严重血小板增多症而反复发生动脉血栓形成的病例。该患者出现了脾脏和肾脏梗死以及腹主动脉血栓形成。随后她接受了铁剂和阿司匹林治疗,贫血和血小板增多症有所改善,未再出现血栓形成并发症。动脉血栓形成是一种非常严重的疾病,因为血栓可栓塞至颈动脉导致中风,或栓塞至外周血管导致外周缺血和坏疽。缺铁性贫血是血小板增多症的一个可逆病因,很容易治疗以避免血栓形成并发症。