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免疫功能正常患者中少动鞘氨醇单胞菌引起的化脓性关节炎:病例报告及文献复习

Septic Arthritis Caused by Sphingomonas Paucimobilis in Immunocompetent Patient: Case Report and Literature Review.

作者信息

Alageel Mohammed K, Alromaih Sarah I, Alzahrani Mohammed T, Abdulsamad Adham M

机构信息

Orthopedics, College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, SAU.

Department of Surgery, Division of Orthopedic Surgery, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, SAU.

出版信息

Cureus. 2022 Feb 13;14(2):e22167. doi: 10.7759/cureus.22167. eCollection 2022 Feb.

DOI:10.7759/cureus.22167
PMID:35308729
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8923253/
Abstract

Septic arthritis, also known as infectious arthritis, is inflammation of the joints due to a wide range of pathogens, such as bacterial, fungal, mycobacterial, viral, or/and other pathogens; however, some opportunistic pathogens tend to affect immunocompromised patients and rarely infect immunocompetent patients. For example, is an opportunistic pathogen with a particular tropism toward bones and soft tissues that rarely causes infections in immunocompetent humans. We present a case of causing septic arthritis in a 34-year-old man who is medically free and with no history of previous surgeries or any other comorbidities. He was treated successfully by both pharmacological treatment and surgical intervention. To our knowledge, there are only four cases published in the literature involving as a causative organism of septic arthritis affecting immunocompetent patients.

摘要

脓毒性关节炎,也称为感染性关节炎,是由多种病原体引起的关节炎症,如细菌、真菌、分枝杆菌、病毒或/和其他病原体;然而,一些机会性病原体往往影响免疫功能低下的患者,很少感染免疫功能正常的患者。例如, 是一种对骨骼和软组织具有特殊嗜性的机会性病原体,很少在免疫功能正常的人类中引起感染。我们报告一例 导致一名34岁男性患脓毒性关节炎的病例,该男性身体健康,既往无手术史或任何其他合并症。通过药物治疗和手术干预,他得到了成功治疗。据我们所知,文献中仅发表了4例涉及 作为导致免疫功能正常患者患脓毒性关节炎的病原体的病例。

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本文引用的文献

1
Sphingomonas paucimobilis-related bone and soft-tissue infections: A systematic review.少动鞘氨醇单胞菌相关的骨和软组织感染:系统评价。
Int J Infect Dis. 2018 Dec;77:68-73. doi: 10.1016/j.ijid.2018.09.021. Epub 2018 Sep 26.
2
Sphingomonas paucimobilis osteomyelitis in an immunocompetent patient. A rare case report and literature review.免疫功能正常患者的少动鞘氨醇单胞菌骨髓炎。一例罕见病例报告及文献综述。
New Microbiol. 2013 Oct;36(4):423-6. Epub 2013 Oct 1.
3
[Septic monarthritis caused by Sphingomonas paucimobilis].少动鞘氨醇单胞菌引起的脓毒性单关节炎
Z Rheumatol. 2013 Oct;72(8):822-6. doi: 10.1007/s00393-013-1237-3.
4
Septic arthritis caused by Sphingomonas paucimobilis in an immunocompetent patient.
Reumatol Clin. 2012 Nov-Dec;8(6):378-9. doi: 10.1016/j.reuma.2012.06.002. Epub 2012 Aug 16.
5
Sphingomonas paucimobilis bacteraemia and septic arthritis in a diabetic patient presenting with septic pulmonary emboli.一名糖尿病患者出现脓毒性肺栓塞,并发少动鞘氨醇单胞菌菌血症和脓毒性关节炎。
J Med Microbiol. 2009 Sep;58(Pt 9):1259-1263. doi: 10.1099/jmm.0.009985-0. Epub 2009 Jun 15.
6
A prospective study of the incidence and characteristics of septic arthritis in a teaching hospital in Riyadh, Saudi Arabia.沙特阿拉伯利雅得一家教学医院中脓毒性关节炎发病率及特征的前瞻性研究。
Clin Rheumatol. 2008 Nov;27(11):1403-10. doi: 10.1007/s10067-008-0934-9. Epub 2008 Jun 27.
7
Bacterial joint infections in England and Wales: analysis of bacterial isolates over a four year period.英格兰和威尔士的细菌性关节感染:四年期间细菌分离株分析
Br J Rheumatol. 1997 Mar;36(3):370-3. doi: 10.1093/rheumatology/36.3.370.