Cheng Joyce, Patel Ghanshyam, Dawood Altaf, Aqeel Ammar
Internal Medicine, Javon Bea Hospital-Riverside, Rockford, USA.
Internal Medicine- Gastroenterology, Javon Bea Hospital-Riverside, Rockford, USA.
Cureus. 2022 Feb 14;14(2):e22208. doi: 10.7759/cureus.22208. eCollection 2022 Feb.
Neuroendocrine tumors (NET) are a small fraction of overall gastrointestinal (GI) malignancies. Recently the incidence of NETs has increased due to advancements in diagnostic modality. While solid tumors are easily visible on routine endoscopy, identifying endocrine tumors can be difficult, and low incidence and non-specific presentation can be easily missed on upper gastrointestinal endoscopy (UGIE). The management differs based on the type of tumor and location, but the overall prognosis is good. We present a 59-year-old male with multiple NETs throughout the GI tract, diagnosed on repeat esophagogastroduodenoscopy (EGD) with endoscopic ultrasound (EUS) showing multiple gastric folds. A biopsy of multiple nodules was taken to diagnose type I NET with grade 2 differentiation finally. The mucosal nodules were resected with a band ligator, and surveillance endoscopy was recommended.
神经内分泌肿瘤(NET)在整个胃肠道(GI)恶性肿瘤中占比很小。近年来,由于诊断方式的进步,NET的发病率有所上升。虽然实体瘤在常规内镜检查中很容易被发现,但识别内分泌肿瘤可能会很困难,而且上消化道内镜检查(UGIE)时,其低发病率和非特异性表现很容易被漏诊。治疗方法因肿瘤类型和位置而异,但总体预后良好。我们报告一名59岁男性,在整个胃肠道有多发性NET,通过重复食管胃十二指肠镜检查(EGD)及内镜超声(EUS)发现多个胃皱襞而确诊。对多个结节进行活检,最终诊断为I型NET,分化程度为2级。用套扎器切除黏膜结节,并建议进行内镜监测。