Ma Jingjing, Jiang Nan, Jiang Zhongtai, Lin Jing, Li Cui, Zhao Guiqiu
Department of Ophthalmology, The Affiliated Hospital of Qingdao University, Qingdao 266003, Shandong, China.
J Ophthalmol. 2022 Mar 8;2022:1614678. doi: 10.1155/2022/1614678. eCollection 2022.
To investigate the difference in anterior segment parameters between suspicious primary angle closure (PACS) patients and normal patients as assessed by ultrasound biomicroscopy (UBM).
From June 2019 to November 2020, 39 patients (50 eyes) with PACS in the Ophthalmology Department of Qingdao University Affiliated Hospital who underwent phacoemulsification and intraocular lens implantation were selected as the PACS group. 32 patients (50 eyes) who underwent phacoemulsification and intraocular lens implantation were selected as the normal group. In addition to routine preoperative examinations such as visual acuity, noncontact intraocular pressure, axis length (AL), and ocular B-ultrasound examination, UBM examinations were also performed, including measuring the central anterior chamber depth (ACD), the maximum transverse diameter of the ciliary process at both ends (STS), the vertical distance between the anterior apex of the lens and the maximum transverse diameter at both ends of the ciliary processes (h), and angle opening distance (AOD500), iris-zonule distance (IZD), trabecular-ciliary process distance (TCPD), trabecular-iris angle (TIA), iris thickness (IT), trabecular-ciliary process angle (TCPA), and anterior placement of the ciliary body (APCB) at four quadrants (superior, nasal, inferior, and temporal quadrants).
Compared with the normal group, the PACS group showed statistically differences in AL, ACD, h, ACD/AL, h/STS, IZD, AOD500, TCPD, TIA, TCPA, and APCB ( < 0.05), and there were no significant differences in STS and IT between the two groups ( > 0.05). In the PACS group, there were significant differences in AL, ACD, h, ACD/AL, h/STS, IZD, TCPD, TCPA, and APCB between PACS patients with zonular relaxation and without zonular relaxation ( < 0.05), while there were no significant differences in STS, AOD500, TIA, and IT ( > 0.05).
UBM quantitatively enables to identify the anterior segment morphology, especially the zonules in patients of suspicious primary angle closure combined with the relaxation of zonule. Accurate measurement of UBM can be used to predict whether patients with PACS are combined with zonular relaxation, so as to provide a clinical imaging evidence for the diagnosis.
通过超声生物显微镜（UBM）评估可疑原发性房角关闭（PACS）患者与正常患者眼前节参数的差异。
选取2019年6月至2020年11月在青岛大学附属医院眼科行白内障超声乳化吸除联合人工晶状体植入术的39例（50只眼）PACS患者作为PACS组。选取32例（50只眼）行白内障超声乳化吸除联合人工晶状体植入术的患者作为正常组。除进行视力、非接触眼压、眼轴长度（AL）、眼部B超等常规术前检查外，还进行UBM检查，包括测量中央前房深度（ACD）、睫状体两端最大横径（STS）、晶状体前顶点与睫状体两端最大横径之间的垂直距离（h）、房角开放距离（AOD500）、虹膜-悬韧带距离（IZD）、小梁-睫状体距离（TCPD）、小梁-虹膜夹角（TIA）、虹膜厚度（IT）、小梁-睫状体夹角（TCPA）以及睫状体在四个象限（上方、鼻侧、下方、颞侧象限）的前位（APCB）。
与正常组相比，PACS组在AL、ACD、h、ACD/AL、h/STS、IZD、AOD500、TCPD、TIA、TCPA和APCB方面差异有统计学意义（<0.05），两组间STS和IT差异无统计学意义（>0.05）。在PACS组中，悬韧带松弛和未松弛的PACS患者在AL、ACD、h、ACD/AL、h/STS、IZD、TCPD、TCPA和APCB方面差异有统计学意义（<0.05），而在STS、AOD500、TIA和IT方面差异无统计学意义（>0.05）。
UBM能够定量识别眼前节形态，尤其是可疑原发性房角关闭患者合并悬韧带松弛时的悬韧带情况。UBM的准确测量可用于预测PACS患者是否合并悬韧带松弛，为诊断提供临床影像学依据。
