Velu Shanmuganathan, Rajagopalan Arul, Arunachalam Jegan, Prasath Arun, Durai Rakesh
Department of Nephrology, Madurai Medical College, Madurai, Tamil Nadu, India.
Int J Nephrol Renovasc Dis. 2022 Mar 14;15:103-114. doi: 10.2147/IJNRD.S351515. eCollection 2022.
Sleep disturbances are common in patients with end-stage kidney disease on hemodialysis (hemodialysis population: HDP). Higher rates of primary sleep disorders, demographic characteristics, metabolic abnormalities, and the efficacy of treatment place HDP at higher risk. The pattern observed is delayed onset of sleep, frequent awakening episodes, insomnia, sleep apnoea, excessive daytime sleepiness, restless leg syndrome, abnormal limb movements, pain in limbs, confusion, and nightmares. Two commonly used subjective assessment scores are the Pittsburgh Sleep Quality Index (PSQI) to assess sleep quality and the Epworth Sleepiness Scale (ESS) to assess excessive daytime sleepiness.
Subjective assessment of sleep using PSQI and ESS scores in HDP and correlation with clinical and demographic characteristics.
A cross-sectional descriptive study of 148 patients with ESKD undergoing in-center hemodialysis. From June 2021 to October 2021 in Madurai medical college, Madurai, India. Subjective assessment with PSQI and ESS scores was done to identify sleep quality and daytime sleepiness, respectively.
The median PSQI score was 6 (IQ:4-10), and as much as 68.24% scored >5 on the PSQI (poor sleepers). The median ESS score of the study participants was 4 (Iq range 3-7), and 19.59% had a total ESS score of more than 10 (excessive daytime sleepiness). The mean age of the participants was 44±14.5. Age more than 60, lower body mass index, unemployment, higher dialysis vintage of more than 2 years, lower hemoglobin, high calcium-phosphorus product are statistically significant for both PSQI and ESS scores.
The prevalence of poor sleep quality and excessive daytime sleepiness is high in HDP. Subjective assessment scores (PSQI and ESS) on the bedside are valuable tools in identifying sleep quality and EDS where objective assessment methods are not feasible and will help in the short time identification and management of sleep disturbances.
睡眠障碍在接受血液透析的终末期肾病患者(血液透析人群:HDP)中很常见。原发性睡眠障碍、人口统计学特征、代谢异常的发生率较高,以及治疗效果使HDP面临更高风险。观察到的模式是睡眠开始延迟、频繁觉醒发作、失眠、睡眠呼吸暂停、白天过度嗜睡、不宁腿综合征、肢体异常运动、肢体疼痛、意识模糊和噩梦。两种常用的主观评估分数是用于评估睡眠质量的匹兹堡睡眠质量指数(PSQI)和用于评估白天过度嗜睡的爱泼华嗜睡量表(ESS)。
使用PSQI和ESS分数对HDP患者的睡眠进行主观评估,并与临床和人口统计学特征进行相关性分析。
对148例在中心接受血液透析的终末期肾病患者进行横断面描述性研究。于2021年6月至2021年10月在印度马杜赖的马杜赖医学院进行。分别使用PSQI和ESS分数进行主观评估,以确定睡眠质量和白天嗜睡情况。
PSQI中位数为6(四分位间距:4 - 10),高达68.24%的患者PSQI得分>5(睡眠质量差)。研究参与者的ESS中位数为4(四分位间距3 - 7),19.59%的患者ESS总分超过10(白天过度嗜睡)。参与者的平均年龄为44±14.5岁。年龄超过60岁、较低的体重指数、失业、透析龄超过2年、较低的血红蛋白、高钙磷乘积对PSQI和ESS分数均具有统计学意义。
HDP患者中睡眠质量差和白天过度嗜睡的患病率很高。床边主观评估分数(PSQI和ESS)是在客观评估方法不可行时识别睡眠质量和白天过度嗜睡的有价值工具,将有助于在短时间内识别和管理睡眠障碍。