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新型冠状病毒肺炎患者肠系膜缺血的综述

Review of Mesenteric Ischemia in COVID-19 Patients.

作者信息

Gupta Amit, Sharma Oshin, Srikanth Kandhala, Mishra Rahul, Tandon Amoli, Rajput Deepak

机构信息

Department of Surgery, All India Institute of Medical Sciences, Level 6, Medical College Block, Rishikesh, Uttarakhand 249203 India.

出版信息

Indian J Surg. 2023 Feb;85(Suppl 1):313-321. doi: 10.1007/s12262-022-03364-w. Epub 2022 Mar 11.

DOI:10.1007/s12262-022-03364-w
PMID:35309713
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8916793/
Abstract

The new coronavirus (COVID-19) infection, first detected in Wuhan, China in 2019 has become a pandemic that has spread to nearly every country in the world. Through October 11, 2021, more than 23 billion confirmed cases and 4.8 million fatalities were reported globally. The bulk of individuals afflicted in India during the first wave were elderly persons. The second wave, however, resulted in more severe diseases and mortality in even younger age groups due to mutations in the wild virus. Symptoms may range from being asymptomatic to fatal acute respiratory distress syndrome (ARDS). In addition to respiratory symptoms, patients may present with gastrointestinal symptoms such as stomach pain, vomiting, loose stools, or mesenteric vein thrombosis. The frequency of patients presenting with thromboembolic symptoms has recently increased. According to certain studies, the prevalence of venous thromboembolism among hospitalized patients ranges from 9 to 25%. It was also shown that the incidence is significantly greater among critically sick patients, with a prevalence of 21-31%. Although the exact origin of thromboembolism is unknown, it is considered to be produced by several altered pathways that manifest as pulmonary embolism, myocardial infarction, stroke, limb gangrene, and acute mesenteric ischemia. Acute mesenteric ischemia (AMI) is becoming an increasingly prevalent cause of acute surgical abdomen in both intensive care unit (ICU) and emergency room (ER) patients. Mesenteric ischemia should be evaluated in situations with unexplained stomach discomfort. In suspected situations, appropriate imaging techniques and early intervention, either non-surgical or surgical, are necessary to avert mortality. The purpose of this article is to look at the data on acute mesenteric ischemia in people infected with COVID-19.

摘要

新型冠状病毒(COVID-19)感染于2019年在中国武汉首次被发现,现已成为一场蔓延至世界几乎每个国家的大流行病。截至2021年10月11日,全球报告的确诊病例超过230亿例,死亡人数达480万。在第一波疫情中,印度受影响的大部分是老年人。然而,由于野生病毒的变异,第二波疫情导致甚至更年轻年龄组出现更严重的疾病和更高的死亡率。症状可能从无症状到致命的急性呼吸窘迫综合征(ARDS)不等。除呼吸道症状外,患者还可能出现胃肠道症状,如胃痛、呕吐、腹泻或肠系膜静脉血栓形成。最近出现血栓栓塞症状的患者频率有所增加。根据某些研究,住院患者中静脉血栓栓塞的患病率在9%至25%之间。研究还表明,危重症患者中的发病率明显更高,患病率为21%至31%。尽管血栓栓塞的确切起源尚不清楚,但人们认为它是由几种改变的途径产生的,表现为肺栓塞、心肌梗死、中风、肢体坏疽和急性肠系膜缺血。急性肠系膜缺血(AMI)正日益成为重症监护病房(ICU)和急诊室(ER)患者急性腹痛的常见原因。在出现不明原因的胃部不适时,应评估是否存在肠系膜缺血。在疑似情况下,需要采用适当的成像技术并进行早期干预,无论是非手术还是手术干预,以避免死亡。本文的目的是研究感染COVID-19的人群中急性肠系膜缺血的数据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78ae/8916793/1ed3a21b7a63/12262_2022_3364_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78ae/8916793/2706eecd80ab/12262_2022_3364_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78ae/8916793/b7ae18f0f0ac/12262_2022_3364_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78ae/8916793/1ed3a21b7a63/12262_2022_3364_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78ae/8916793/2706eecd80ab/12262_2022_3364_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78ae/8916793/b7ae18f0f0ac/12262_2022_3364_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78ae/8916793/1ed3a21b7a63/12262_2022_3364_Fig3_HTML.jpg

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