Kitahara Yoshihiro, Taniyama Daiki, Kuraoka Kazuya, Saito Akihisa, Zaitsu Junichi, Oga Kenichi, Senoo Misato, Araki Yusuke, Yamaguchi Atsushi, Nakano Kikuo
Department of Respiratory Medicine, National Hospital Organization Kure Medical Center and Chugoku Cancer Center, Hiroshima, Japan.
Department of Diagnostic Pathology, National Hospital Organization Kure Medical Center and Chugoku Cancer Center, Hiroshima, Japan.
Respir Med Case Rep. 2022 Mar 11;37:101621. doi: 10.1016/j.rmcr.2022.101621. eCollection 2022.
A 61-year-old woman was admitted to our hospital with productive cough and fever. Computed tomography images revealed ground glass opacities in both lung fields, and a space-occupying lesion in the gallbladder. Transbronchial lung biopsy revealed a poorly differentiated adenocarcinoma with invasion of the lymph ducts; accordingly, a diagnosis of lymphangitis carcinomatosa was made. We could not administer chemotherapy due to poor performance status, and the patient died of respiratory failure 30 days after admission. Owing to pathological autopsy findings of poorly differentiated adenocarcinoma in the gallbladder, we diagnosed this as a rare case of gallbladder cancer presenting with lymphangitis carcinomatosa.
一名61岁女性因咳痰和发热入院。计算机断层扫描图像显示双肺野磨玻璃影,胆囊有占位性病变。经支气管肺活检显示低分化腺癌伴淋巴管侵犯;因此,诊断为癌性淋巴管炎。由于患者身体状况较差,无法进行化疗,患者入院30天后死于呼吸衰竭。根据胆囊低分化腺癌的病理尸检结果,我们将此诊断为罕见的以癌性淋巴管炎为表现的胆囊癌病例。