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胆囊癌所致癌性淋巴管炎

Lymphangitis carcinomatosa from gallbladder cancer.

作者信息

Kitahara Yoshihiro, Taniyama Daiki, Kuraoka Kazuya, Saito Akihisa, Zaitsu Junichi, Oga Kenichi, Senoo Misato, Araki Yusuke, Yamaguchi Atsushi, Nakano Kikuo

机构信息

Department of Respiratory Medicine, National Hospital Organization Kure Medical Center and Chugoku Cancer Center, Hiroshima, Japan.

Department of Diagnostic Pathology, National Hospital Organization Kure Medical Center and Chugoku Cancer Center, Hiroshima, Japan.

出版信息

Respir Med Case Rep. 2022 Mar 11;37:101621. doi: 10.1016/j.rmcr.2022.101621. eCollection 2022.

DOI:10.1016/j.rmcr.2022.101621
PMID:35309973
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8927845/
Abstract

A 61-year-old woman was admitted to our hospital with productive cough and fever. Computed tomography images revealed ground glass opacities in both lung fields, and a space-occupying lesion in the gallbladder. Transbronchial lung biopsy revealed a poorly differentiated adenocarcinoma with invasion of the lymph ducts; accordingly, a diagnosis of lymphangitis carcinomatosa was made. We could not administer chemotherapy due to poor performance status, and the patient died of respiratory failure 30 days after admission. Owing to pathological autopsy findings of poorly differentiated adenocarcinoma in the gallbladder, we diagnosed this as a rare case of gallbladder cancer presenting with lymphangitis carcinomatosa.

摘要

一名61岁女性因咳痰和发热入院。计算机断层扫描图像显示双肺野磨玻璃影,胆囊有占位性病变。经支气管肺活检显示低分化腺癌伴淋巴管侵犯;因此,诊断为癌性淋巴管炎。由于患者身体状况较差,无法进行化疗,患者入院30天后死于呼吸衰竭。根据胆囊低分化腺癌的病理尸检结果,我们将此诊断为罕见的以癌性淋巴管炎为表现的胆囊癌病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b9d/8927845/e700d24af7bb/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b9d/8927845/daa1fc008bed/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b9d/8927845/e28ffe27217f/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b9d/8927845/9bfd33c92d3e/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b9d/8927845/77790592f589/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b9d/8927845/8863679b2caf/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b9d/8927845/a6fc81668579/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b9d/8927845/2d92971cb549/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b9d/8927845/e700d24af7bb/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b9d/8927845/daa1fc008bed/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b9d/8927845/e28ffe27217f/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b9d/8927845/9bfd33c92d3e/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b9d/8927845/77790592f589/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b9d/8927845/8863679b2caf/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b9d/8927845/a6fc81668579/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b9d/8927845/2d92971cb549/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b9d/8927845/e700d24af7bb/gr8.jpg

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本文引用的文献

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Pulmonary lymphangitic carcinomatosis from gallbladder cancer mimicking diffuse alveolar haemorrhage.胆囊癌所致肺淋巴管癌病酷似弥漫性肺泡出血
Respirol Case Rep. 2020 Feb 17;8(3):e00540. doi: 10.1002/rcr2.540. eCollection 2020 Apr.
2
Pulmonary lymphangitis carcinomatosis: systematic review and meta-analysis of case reports, 1970-2018.肺淋巴管癌病:1970-2018 年病例报告的系统评价和荟萃分析。
Postgrad Med. 2019 Jun;131(5):309-318. doi: 10.1080/00325481.2019.1595982. Epub 2019 Apr 5.
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Gallbladder cancer epidemiology, pathogenesis and molecular genetics: Recent update.
胆囊癌的流行病学、发病机制及分子遗传学:最新进展
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Eosinophilia.嗜酸性粒细胞增多
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Gallbladder cancer: epidemiology and outcome.胆囊癌:流行病学与预后
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Lymphangitis carcinomatosa: report of a case and review of literature.癌性淋巴管炎:一例报告及文献综述
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Utility of KL-6/MUC1 in the clinical management of interstitial lung diseases.KL-6/MUC1在间质性肺疾病临床管理中的应用
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Cisplatin plus gemcitabine versus gemcitabine for biliary tract cancer.顺铂联合吉西他滨与吉西他滨治疗胆管癌。
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Lymphangitis carcinomatosa.癌性淋巴管炎
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