Okamura Takuma, Iwaya Yugo, Nagaya Tadanobu, Muranaka Futoshi, Ota Hiroyoshi, Umemura Takeji
Department of Gastroenterology Shinshu University School of Medicine Nagano Japan.
Department of Surgery Shinshu University School of Medicine Nagano Japan.
DEN Open. 2021 Aug 22;2(1):e16. doi: 10.1002/deo2.16. eCollection 2022 Apr.
Gastric hamartomatous inverted polyp (GHIP) is rare, with few reports of carcinogenesis from GHIP during long-term follow-up. A 51-year-old woman was diagnosed as having a submucosal tumor (SMT) during esophagogastroduodenoscopy (EGD) in 2008. In 2016, although the size and height of the lesion had not changed, she was referred to our hospital for further investigation of the lesion. EGD depicted a gastric SMT of 20 mm in diameter in the greater curvature of the upper gastric body, and a biopsy specimen showed a well to poorly differentiated adenocarcinoma. Following successful laparoscopic total gastrectomy, histopathological examination revealed an intramucosal adenocarcinoma arising in GHIP.
胃错构瘤性内翻息肉（GHIP）较为罕见，长期随访中关于GHIP发生癌变的报道较少。一名51岁女性在2008年的食管胃十二指肠镜检查（EGD）中被诊断为患有黏膜下肿瘤（SMT）。2016年，尽管病变的大小和高度没有变化，但她因病变进一步检查被转诊至我院。EGD显示胃体上部大弯处有一个直径20mm的胃SMT，活检标本显示为高分化至低分化腺癌。在成功进行腹腔镜全胃切除术后，组织病理学检查显示为GHIP内发生的黏膜内腺癌。
