Ometto A, Fazzi E
Ital J Neurol Sci. 1986 Apr;Suppl 5:79-83.
In the Pavia Neonatal Intensive Care Unit all newborns at risk for brain damage have, since 1983, undergone transfontanellar ultrasound scanning regularly for the early diagnosis of hemorrhage and/or anoxia-ischemia. They have also been assessed clinically by a child neuropsychiatrist during the hospital stay and every two months at outpatients' for the first year of life as a check on the prognostic value of ultrasound scanning. The results relating to a sample of 56 at risk newborns, with normal and abnormal ultrasound scans, who have now reached 12 months corrected age are reported. A normal ultrasound scan presupposes normal neuropsychic development in 87% of cases, as happens in the event of uncomplicated hemorrhage. Major sequelae occur in as many as 83% of cases of complicated hemorrhage. The diagnosis of severe anoxia-ischemia likewise argues for a pathological neuropsychic development. Our results convince us that transfontanellar ultrasound scanning is an indispensable tool not only for the early diagnosis of brain damage but also as a guide to prognosis in the newborn at risk.
自1983年以来,在帕维亚新生儿重症监护病房,所有有脑损伤风险的新生儿都定期接受经囟门超声扫描,以早期诊断出血和/或缺氧缺血。在住院期间,儿童神经精神科医生对他们进行了临床评估,在出生后的第一年,每两个月在门诊进行一次评估,以检查超声扫描的预后价值。报告了56例有风险新生儿的样本结果,这些新生儿的超声扫描结果有正常和异常之分,他们现在已达到12个月的矫正年龄。超声扫描正常意味着在87%的病例中神经精神发育正常,这与单纯性出血的情况相同。在83%的复杂性出血病例中会出现严重后遗症。严重缺氧缺血的诊断同样表明神经精神发育存在病理情况。我们的结果使我们相信,经囟门超声扫描不仅是早期诊断脑损伤的不可或缺的工具,也是有风险新生儿预后的指导依据。