College of Chemistry, and Institute of Green Catalysis, Zhengzhou University, Zhengzhou, Henan 450001, China.
Shanghai-Hong Kong Joint Laboratory in Chemical Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, The Chinese Academy of Sciences, Shanghai 200032, China.
Inorg Chem. 2022 Apr 4;61(13):5326-5334. doi: 10.1021/acs.inorgchem.2c00074. Epub 2022 Mar 21.
The B(9)-H halogenation of -carborane and -carborane was achieved with excellent selectivities in hexafluoroisopropanol (HFIP) under simple reaction conditions: single reagent [trichloroisocyanuric acid (TCCA), tribromoisocyanuric acid (TBCA) or -iodosuccinimide (NIS)], catalyst-free, air-/moisture-tolerant, and convenient work-up. With this method, a variety of 9-halogenated -carboranes and -carboranes were obtained in good to excellent yields with broad tolerance of functional groups.
