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[妊娠患者的内科急症:围产期败血症、代谢紊乱、内分泌急症及肺水肿]

[Internal medical emergencies in the pregnant patient : Peripartum sepsis, metabolic derailment, endocrinological emergencies and pulmonary edema].

作者信息

Fischer J, Gerresheim G, Schwemmer U

机构信息

Klinik für Anästhesiologie und Intensivmedizin, Klinikum Neumarkt i.d.OPf., Neumarkt i.d.OPf., Deutschland.

出版信息

Med Klin Intensivmed Notfmed. 2022 Apr;117(3):239-252. doi: 10.1007/s00063-022-00910-y.

Abstract

Peripartum emergencies that require intensive medical care represent a major challenge for the interdisciplinary treatment team. Due to physiological changes in pregnant women symptoms can be masked and the initiation of treatment is delayed. Peripartum sepsis has a relatively high incidence. The anti-infective treatment depends on the spectrum of pathogens to be expected. Endocrinological emergencies are rare but can be fulminant and fatal. The development of ketoacidosis is favored by decreased bicarbonate buffer and placental hormones. In the case of thyrotoxicosis, propylthiouracil and thiamazole are available for treatment depending on the stage of gestation. Sheehan's syndrome is an infarction of the anterior lobe of the pituitary gland during a hemorrhage. Due to the loss of production of vital hormones, this can be fatal. The development of pulmonary edema is just as acute. This is favored by physiological changes during pregnancy. The differentiation between hypertensive and hypotensive pulmonary edema is important for the causal treatment.

摘要

需要重症医疗护理的围产期紧急情况对多学科治疗团队来说是一项重大挑战。由于孕妇的生理变化,症状可能被掩盖,治疗开始时间会延迟。围产期败血症发病率相对较高。抗感染治疗取决于预期的病原体谱。内分泌紧急情况很少见,但可能是暴发性且致命的。碳酸氢盐缓冲液减少和胎盘激素会促使酮症酸中毒的发生。对于甲状腺毒症,根据妊娠阶段可使用丙硫氧嘧啶和甲巯咪唑进行治疗。席汉综合征是指垂体前叶在出血期间发生梗死。由于重要激素分泌丧失,这可能是致命的。肺水肿的发展同样迅速。这受到孕期生理变化的影响。区分高血压性和低血压性肺水肿对于病因治疗很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f54c/8935102/5e745784bf3d/63_2022_910_Fig1_HTML.jpg

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