Adana City Training and Research Hospital, Department of Emergency Medicine, Adana, Turkey.
J Forensic Leg Med. 2022 Apr;87:102335. doi: 10.1016/j.jflm.2022.102335. Epub 2022 Mar 17.
Acetamiprid is a member of neonicotinoid insecticides with a low risk of toxicity in humans. However, ingestion of large amounts may cause severe poisoning. This is the first case reported in the literature in which severe toxicity and death occurred after acetamiprid ingestion. A 57-year-old male patient consumed 50g/250mL of an insecticide formulation containing acetamiprid for suicidal purposes. The ambulance team performed cardiopulmonary resuscitation on the patient who had a cardiac arrest. His heart beat returned after a 15-min cardiopulmonary resuscitation, and afterward, he had tachycardia, hypotension, respiratory failure, high gap metabolic acidosis with a high lactate, hypokalemia, hypocalcemia, mydriasis, and coma. The patient underwent supportive treatment for a variety of symptoms. However, he died despite all supportive treatment. This case demonstrates that ingestion of large amounts of the acetamiprid and late presentation can be fatal despite all supportive care.
乙酰甲胺磷是一种低毒的新烟碱类杀虫剂。然而,大量摄入可能会导致严重中毒。这是文献中首次报道的乙酰甲胺磷摄入后发生严重毒性和死亡的病例。一名 57 岁男性患者出于自杀目的摄入了 50g/250mL 的含有乙酰甲胺磷的杀虫剂制剂。救护车团队对发生心脏骤停的患者进行了心肺复苏。心肺复苏 15 分钟后,他的心跳恢复,随后出现心动过速、低血压、呼吸衰竭、高间隙代谢性酸中毒伴高乳酸血症、低钾血症、低钙血症、瞳孔散大及昏迷。患者接受了针对各种症状的支持性治疗。然而,尽管进行了所有的支持性治疗,他还是死亡了。本例表明,摄入大量的乙酰甲胺磷和延迟就诊即使进行所有的支持性治疗也可能致命。