BACKGROUND: Coronavirus is an emerging respiratory pathogen that causes coronavirus disease-2019 (COVID-19), as per the Chinese Center for Disease Control and Prevention. OBJECTIVE: This study aimed to assess the state of awareness and extent of knowledge about COVID-19 among dental students from India, Pakistan, and Saudi Arabia. MATERIALS AND METHODS: The present descriptive cross-sectional study was conducted on 872 participants from December 2020 to January 2021. Random sampling was performed using an electronic questionnaire. One-way analysis of variance and independent sample t-test were performed to assess and compare the mean knowledge score between different demographic data. RESULTS: Approximately 60% (n = 520) of the responders were women and 40% responders were men (n = 352). The responders were from Saudi Arabia (36.9%; n = 322), India (34.2%; n = 298), and Pakistan (28.8%; n = 252). The difference within the subgroups was statistically nonsignificant (P > 0.05), indicating that dental students of all subparameters possessed equal knowledge on COVID-19. CONCLUSIONS: Dental students possess sufficient knowledge about COVID-19, qualifying them at least to work in a medical ward. However, more emphasis must be placed on infection prevention and control policies such as hand hygiene, personal protective equipment, and pre- and postexposure prophylaxis.