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中国智能影像传感器联合视觉训练治疗间歇性外斜视的临床效果的对比剂和分子影像学荟萃分析。

Contrast Agent and Molecular Imaging Meta-Analysis of the Clinical Effect of Intelligent Image Sensor Combined with Visual Training in the Treatment of Children with Intermittent Exotropia in China.

机构信息

Chinese Medicine Ophthalmology, Hebei University of Chinese Medicine, Hebei Provincial Hospital of Traditional Chinese Medicine, Shijiazhuang 050000, Hebei, China.

Chinese Medicine Ophthalmology, Hebei Provincial Hospital of Traditional Chinese Medicine, Shijiazhuang 050000, Hebei, China.

出版信息

J Healthc Eng. 2022 Mar 12;2022:5387928. doi: 10.1155/2022/5387928. eCollection 2022.

Abstract

At present, the main treatment for strabismus is still surgical treatment, but there is no unified standard for the evaluation of the timing of surgery. This study mainly explores the clinical effects of using meta-analysis of intelligent image sensors combined with visual training to treat children with intermittent exotropia. Cochrane systematic reviews collect, evaluate, and synthesize an increasing number of original clinical research results to obtain the comprehensive effect of relevant interventions, so as to provide real and reliable evidence for health decision-making and clinical practice. It uses scientific, clear, and reproducible research methods to reduce the influence of biased factors, so it is different from traditional reviews. Cochrane systematic reviews are especially suitable for certain interventions when the pros and cons of interventions are difficult to determine based on the results of a single clinical study or when there are large differences in the clinical application process. Poor quality systematic reviews can mislead policymakers and clinicians. In the meta-analysis, the Cochrane systematic evaluation method of evidence-based medicine was used to comprehensively search the published literature research on the treatment of intermittent exotropia with vision training. Using the Cochrane system evaluation method, computer search of CENTRAL, MEDLINE, Embase, Chinese Biomedical Literature Database, Chinese Journal Full-text Database, manual retrieval of relevant conference documents, and inclusion of all clinical trial documents of visual training in children with intermittent exotropia was conducted. Patients with intermittent exotropia were selected, simultaneous vision, fusion function, and far stereo vision with the same vision machine were measured, and near stereo vision with a stereo vision chart was measured. The number of simultaneous vision, fusion function, and distance and near stereo vision "with" and "without" cases were recorded for all patients, and the relationship with age of onset, type of strabismus, degree of strabismus, and degree of control was counted. Among them, 91 patients who underwent strabismus correction surgery were followed up for at least 6 months with correct eye position. The presence or absence of simultaneous vision, fusion function, far stereo vision, and near stereo vision were recorded and compared with preoperative. The number of recovery and nonrecovery cases was recorded, and the relationship between the age of operation, the type of strabismus, the degree of strabismus, and the degree of control was counted. It was statistically analyzed by SPSS22.0. The results of the meta-analysis showed that in terms of the effective rate of fundus lesions, the visual training group was better than the nontraining group, and the difference between the two groups was statistically significant (RR = 1.32, 95% CI: (1.25, 1.40),  < 0.0001). This study provides guidance for the early rehabilitation of children with intermittent exotropia.

摘要

目前,斜视的主要治疗方法仍是手术治疗,但手术时机的评估尚无统一标准。本研究主要探讨应用智能图像传感器结合视觉训练治疗儿童间歇性外斜视的临床效果。Cochrane 系统评价收集、评价和综合越来越多的原始临床研究结果,以获得相关干预措施的综合效果,从而为卫生决策和临床实践提供真实可靠的证据。它使用科学、明确和可重复的研究方法来减少偏倚因素的影响,因此与传统评价不同。Cochrane 系统评价尤其适用于某些干预措施,当基于单个临床研究结果难以确定干预措施的优缺点,或临床应用过程中存在较大差异时。质量差的系统评价会误导决策者和临床医生。在荟萃分析中,采用循证医学 Cochrane 系统评价方法,全面检索视觉训练治疗间歇性外斜视的已发表文献研究。使用 Cochrane 系统评价方法,计算机检索 CENTRAL、MEDLINE、Embase、中国生物医学文献数据库、中国期刊全文数据库,手工检索相关会议文献,并纳入所有儿童间歇性外斜视视觉训练的临床研究文献。选择间歇性外斜视患者,使用同视机测量同时视、融合功能和远立体视,使用立体视觉图表测量近立体视。记录所有患者的同时视、融合功能、距离和近立体视“有”和“无”例数,并与发病年龄、斜视类型、斜视程度和控制程度进行计数。其中,91 例行斜视矫正手术的患者至少随访 6 个月,正位眼位。记录同时视、融合功能、远立体视和近立体视的存在或缺失情况,并与术前比较。记录恢复和未恢复的例数,并与手术年龄、斜视类型、斜视程度和控制程度进行计数。采用 SPSS22.0 进行统计学分析。荟萃分析结果显示,眼底病变有效率方面,视觉训练组优于非训练组,两组差异有统计学意义(RR=1.32,95%CI:(1.25,1.40),<0.0001)。本研究为儿童间歇性外斜视的早期康复提供了指导。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0980/8934207/113c6426fb04/JHE2022-5387928.001.jpg

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