Subota Ann, Spotswood Neve, Roach Maddy, Goodarzi Zahra, Holroyd-Leduc Jayna
Department of Medicine, University of Calgary, Calgary, Alberta, Canada.
Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
Can J Aging. 2022 Dec;41(4):540-549. doi: 10.1017/S071498082100060X. Epub 2022 Mar 22.
Caregivers of persons with dementia and depression experience adverse effects associated with their role. The aim of this scoping review was to identify the challenges faced by caregivers of people with dementia and depression, along with interventions to support them. The MEDLINE®, Embase and PsycINFO databases were searched using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) method. Grey literature was assessed using the Canadian Agency for Drugs and Technologies in Health's Gray Matter tool.The population consisted of caregivers of people with dementia and depression; the concept was to identify the negative impacts that caregivers experience and whether there are interventions to reduce them; the context was any study design targeting family or friends who were caregivers. A total of 12,835 citations were identified; 139 studies were included. Dementia and depression have variable impacts on outcomes experienced by caregivers, including burden/strain ( = 52), depression ( = 27), distress ( = 53), quality of life ( = 5) and health/well-being ( = 9). Pharmacological and non-pharmacological interventions have mixed effects. This study is important considering that depression in people with dementia is associated with caregiver distress. The use of a variety of non-pharmacological interventions could be beneficial to the latter.
患有痴呆症和抑郁症患者的照料者会经历与其角色相关的不良影响。本范围综述的目的是确定痴呆症和抑郁症患者的照料者所面临的挑战，以及支持他们的干预措施。使用系统评价和Meta分析的首选报告项目（PRISMA）方法检索了MEDLINE®、Embase和PsycINFO数据库。使用加拿大卫生药物和技术局的“灰色物质”工具对灰色文献进行了评估。研究对象为痴呆症和抑郁症患者的照料者；研究概念是确定照料者所经历的负面影响以及是否存在减轻这些影响的干预措施；研究背景是针对作为照料者的家人或朋友的任何研究设计。共识别出12835条引文；纳入了139项研究。痴呆症和抑郁症对照料者所经历的结果有不同影响，包括负担/压力（n = 52）、抑郁（n = 27）、痛苦（n = 53）、生活质量（n = 5）和健康/幸福感（n = 9）。药物和非药物干预的效果不一。鉴于痴呆症患者的抑郁与照料者的痛苦相关，本研究具有重要意义。使用多种非药物干预措施可能对后者有益。
