Department of Neuroradiology, University Hospital San Giovanni di Dio e Ruggi d'Aragona, University of Salerno, Salerno, Italy.
Department of Neuroradiology, University Hospital San Giovanni di Dio e Ruggi d'Aragona, University of Salerno, Salerno, Italy.
World Neurosurg. 2022 Jun;162:10. doi: 10.1016/j.wneu.2022.03.045. Epub 2022 Mar 18.
Extracranial artery dissections (EADs) represent leading causes of stroke in young patients, but are uncommon in the general population, thus making it challenging to conduct clinical trials and large observational studies. In this technical video, we present 2 adult patients with cervical internal carotid artery (ICA) dissection treated with flow diverters (Video 1). The first patient come to our attention without symptoms. He had a history of acute ischemic stroke owing to dissection of the right cervical ICA in 2013. He was on double antiplatelet therapy, and he had recurrent colorectal bleeding. Magnetic resonance imaging confirmed right frontal gliosis and occlusion of the right ICA with collaterals from the external carotid artery and showed a double lumen dissection of the left cervical ICA. The second patient was admitted to our emergency department with right tongue and vocal cord palsy. Computed tomography documented 2 carotid pseudoaneurysms, the bigger one on the right side. Flow diversion was successful in both patients. In 15%-20% of patients with EAD, multiple cervical arteries are affected. In EAD, stenosis resolution or recanalization occurs in 33%-90% of patients within 6 months. Dissecting aneurysms are reported to resolve or decrease in size in 40%-50% of patients, but can also increase in size. There are currently no controlled clinical trials comparing endovascular therapy and antithrombotic treatment with antithrombotic therapy alone in patients with carotid EAD, and only some reports have demonstrated the efficacy of angioplasty and stenting. However, we recommend some further reading on this topic..
颅外动脉夹层 (EAD) 是年轻患者中风的主要原因,但在普通人群中并不常见,因此难以开展临床试验和大型观察性研究。在这个技术视频中,我们介绍了 2 例接受血流导向装置治疗的颈内动脉 (ICA) 夹层患者(视频 1)。第 1 位患者因 2013 年右侧颈内动脉夹层导致急性缺血性中风而引起我们的关注。他正在接受双联抗血小板治疗,并且反复出现结直肠出血。磁共振成像证实右侧额叶胶质增生和右侧 ICA 闭塞,并有来自颈外动脉的侧支循环,显示左侧颈内动脉双腔夹层。第 2 位患者因右侧舌和声带麻痹被收入我们的急诊科。计算机断层扫描显示 2 个颈动脉假性动脉瘤,较大的一个位于右侧。在这 2 位患者中,血流导向装置治疗均获得成功。在 15%-20%的 EAD 患者中,多条颈内动脉受累。在 EAD 中,33%-90%的患者在 6 个月内狭窄缓解或再通。报道称,40%-50%的夹层动脉瘤会缓解或缩小,但也可能增大。目前,在颈动脉 EAD 患者中,尚无比较血管内治疗与抗血栓治疗与单纯抗血栓治疗的对照临床试验,仅有一些报告显示血管成形术和支架置入术的疗效。然而,我们推荐进一步阅读本专题的文献。