Hepatogastroenterology Unit, Second Department of Internal Medicine-Propaedeutic, Attikon University General Hospital, National and Kapodistrian University of Athens Medical School, Athens, Greece.
Department of Gastroenterology and Hepatology, Radboud University Medical Center, Nijmegen, the Netherlands.
Gut Liver. 2022 Sep 15;16(5):667-675. doi: 10.5009/gnl210327. Epub 2022 Mar 22.
Gastric outlet obstruction (GOO) is a relatively common condition in which mechanical obstruction of the pylorus, distal stomach, or duodenum causes severe symptoms such as nausea, vomiting, abdominal pain, and early satiety. Its etiology includes both benign and malignant disorders. Currently, GOO has many treatment options, including initial conservative therapeutic protocols and more invasive procedures, such as surgical gastroenterostomy, stent placement and, the most recently implemented procedure, endoscopic ultrasound-guided gastroenterostomy (EUS-GE). Each procedure has its merits, with surgery often prevailing in patients with longer life expectancy and stents being used most often in patients with malignant gastric outlet stenosis. The newly developed EUS-GE combines the immediate effect of stents and the long-term efficacy of gastroenterostomy. However, this novel method is a technically demanding process that requires expert experience and special facilities. Thus, the true clinical effectiveness, as well as the duration of the effects of EUS-GE, still need to be determined.
胃出口梗阻（GOO）是一种较为常见的病症，其特征为幽门、胃远端或十二指肠机械性梗阻，导致严重的恶心、呕吐、腹痛和早饱等症状。其病因既有良性也有恶性。目前，GOO 有许多治疗选择，包括初始的保守治疗方案和更具侵袭性的程序，如外科胃空肠吻合术、支架置入术，以及最近实施的内镜超声引导下胃空肠吻合术（EUS-GE）。每种方法都有其优点，手术通常适用于预期寿命较长的患者，支架置入术则常用于恶性胃出口狭窄的患者。新开发的 EUS-GE 结合了支架的即时效果和胃空肠吻合术的长期效果。然而，这种新方法是一个技术要求很高的过程，需要专家经验和特殊设备。因此，EUS-GE 的真正临床效果及其效果持续时间仍有待确定。
