Department of Applied Chemistry, Aichi Institute of Technology, 1247 Yachigusa, Yakusa-cho, Toyota, 470-0392, Japan.
School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, 192-0392, Japan.
Anal Sci. 2022 Feb;38(2):307-315. doi: 10.2116/analsci.21P265. Epub 2022 Mar 22.
A fabrication method of molding-type solid-phase extraction media (M-SPEM) bound with commercially available adhesive is presented. Six pieces of M-SPEM were prepared by heating each kneaded product of a particulate sorbent and an adhesive inserted into a six-hole cylindrical mold for hardening under an open system and normal pressure. The particulate sorbent contained in M-SPEM was divinylbenzene-based reversed-phase mode solid-phase extractants that we have reported. An examination of several adhesives showed that the moldability of M-SPEM depended on the composition and properties of the adhesive. The optimized procedure can be used to prepare an M-SPEM containing an 85 wt% particulate sorbent (particulate sorbent/adhesive, 100 mg/17 mg; particle diameter, 90-150 µm), and the M-SPEM has a specific surface area of about 500 m/g. The established procedure in this study can bind particulate sorbents together, which showed almost no reductions in the adsorption property and liquid permeability compared with those of the particulate sorbent.
本文介绍了一种采用市售黏合剂制备模压型固相萃取介质（M-SPEM）的方法。将颗粒状吸附剂和黏合剂的混合物加热后放入六孔圆柱形模具中，在开放体系和常压下进行硬化，得到 6 个 M-SPEM。M-SPEM 中所含的颗粒状吸附剂为我们之前报道的基于二乙烯基苯的反相模式固相萃取剂。对几种黏合剂的考察表明，M-SPEM 的可模塑性取决于黏合剂的组成和性质。优化后的程序可用于制备一种含有 85wt%颗粒状吸附剂的 M-SPEM（颗粒状吸附剂/黏合剂，100mg/17mg；粒径，90-150µm），M-SPEM 的比表面积约为 500m/g。本研究中建立的程序可以将颗粒状吸附剂结合在一起，与颗粒状吸附剂相比，其吸附性能和液体渗透性几乎没有降低。
