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严重血友病儿童参加竞技运动的医学认证资格:意大利观察性研究。

Eligibility for competitive sport medical certification of children with severe hemophilia: Italian observational study.

机构信息

Pediatric Unit, Department of Biomedical Science and Human Oncology, University of Bari "Aldo Moro", Bari, Italy.

Sports Medicine Institute "Vito Accettura", Italian Sports Medicine Federation, Bari, Italy.

出版信息

Acta Biomed. 2022 Mar 14;93(1):e2022129. doi: 10.23750/abm.v93i1.11531.

Abstract

Background ad aim of workː the position of Italian law regarding participation of prophylactically treated hemophiliacs to organized sport trainings and competitions remains unclear and this study focuses on the eligibility of pediatric patients in particular. Methodsː 16 patients age 3 to 15 years old, with severe haemophilia and prophylaxis starting age of 20,2 ± 2,2 months were enrolled. Weight, height, body mass index (BMI) and joint status (Hemophilia Joint Health Score [HJHS] and Haemophilia Early Arthropathy Detection with UltraSound, HEAD-US score) of patients were evaluated at start (T0) and after 12 months (T12) of a HIITS sport activity program. Resultsː All patients qualified for Italian competitive sport medical certification. Their weight and height increased after 12 months, without an increase in BMI (T0= 17,2; T1= 18,7; p>0,05). HJHS score did not change significantly (T0: 1.6 ± 1; T1: 2.1 ± 1.3; p>0.05). All children were right-handed and atrophy for the muscles of the right elbow significantly decreased (no atrophy seen at T0 in 4 of 16 patients and at T1 in 8 of 16 patients; p=0.045). Conclusionsː Hemophilic children, prophylactically treated, are capable to be included in sport groups and physical activity programs.

摘要

背景与工作目的

意大利法律关于预防性治疗血友病患者参与有组织的体育训练和比赛的立场仍不清楚,本研究特别关注儿科患者的资格。方法:纳入了 16 名年龄在 3 至 15 岁、接受预防性治疗且起始年龄为 20.2±2.2 个月的重度血友病患儿。在 HIITS 运动项目开始时(T0)和 12 个月后(T12),评估患者的体重、身高、体质量指数(BMI)和关节状况(血友病关节健康评分[HJHS]和超声早期血友病关节炎检测,HEAD-US 评分)。结果:所有患者均符合意大利竞技体育医学认证的要求。他们的体重和身高在 12 个月后增加,而 BMI 没有增加(T0=17.2;T1=18.7;p>0.05)。HJHS 评分无显著变化(T0:1.6±1;T1:2.1±1.3;p>0.05)。所有患儿均为右利手,右侧肘部肌肉萎缩明显减少(16 例患儿中,T0 时无 4 例患儿出现萎缩,T1 时 8 例患儿出现萎缩;p=0.045)。结论:预防性治疗的血友病患儿有能力参加体育团体和体育活动项目。

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WFH Guidelines for the Management of Hemophilia, 3rd edition.《血友病管理的居家指南》第三版
Haemophilia. 2020 Aug;26 Suppl 6:1-158. doi: 10.1111/hae.14046. Epub 2020 Aug 3.
2
Perceived well-being and mental health in haemophilia.血友病患者的幸福感和心理健康。
Psychol Health Med. 2020 Oct;25(9):1062-1072. doi: 10.1080/13548506.2020.1717556. Epub 2020 Jan 26.
4
Gene therapy for hemophilia: Progress to date and challenges moving forward.血友病的基因治疗:迄今的进展与未来面临的挑战
Transfus Apher Sci. 2019 Oct;58(5):602-612. doi: 10.1016/j.transci.2019.08.012. Epub 2019 Aug 6.
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Establishing an online physical exercise program for people with hemophilia.为血友病患者建立在线体育锻炼项目。
Wien Klin Wochenschr. 2019 Nov;131(21-22):558-566. doi: 10.1007/s00508-019-01548-1. Epub 2019 Sep 18.
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How I approach managing student athletes at risk for bleeding.我如何管理有出血风险的运动员学生。
Pediatr Blood Cancer. 2019 Feb;66(2):e27523. doi: 10.1002/pbc.27523. Epub 2018 Oct 26.

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