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拔牙后严重感染——我们在预防方面做得够吗?

Severe infections after teeth removal - are we doing enough in preventing them?

作者信息

Rautaporras Niina, Uittamo Johanna, Furuholm Jussi, Snäll Johanna

机构信息

DDS, Department of Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

MD, DDS, PhD, Department of Oral and Maxillofacial Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

出版信息

J Clin Exp Dent. 2022 Mar 1;14(3):e254-e262. doi: 10.4317/jced.59314. eCollection 2022 Mar.

Abstract

BACKGROUND

The present study clarified features and prehospital care in patients with severe infection after teeth removal.

MATERIAL AND METHODS

Patients who were hospitalized for infection following teeth removal were included in this study. Background variables and infection severity parameters were compared between patients who underwent elective and acute teeth removal prior to hospitalization. Additionally, associations of these variables with antibiotic use were evaluated.

RESULTS

Of the 118 patients included in the study, teeth removal was due to acute infection in 64% and removal was elective in 36%. The time span from teeth removal to hospitalization varied considerably (from <1 day to 205 days). The variation was significantly greater in patients with preceding acute removal than those with elective removal (=0.030). Smoking was significantly associated with acute teeth removal (<0.001). Length of hospital stay (LOHS) was a day longer in the elective group (=0.017). Overall, 70% of patients received antibiotics prior to hospitalization. There was a significant association between removal type and antibiotic use (=0.005); antibiotic use was less common in elective teeth removal patients. Immunocompromised patients received antibiotic prophylaxis significantly more often than non-immunocompromised patients (=0.003). LOHS was significantly associated with prehospital antibiotic use (=0.035). LOHS was a day longer in patients who had not received antibiotics than in other patients.

CONCLUSIONS

Severe infection can develop with a long delay after acute teeth removal. More attention should be paid to preceding symptoms and early effective treatment of these infections. A more precise timing of antibiotic use could reduce severe postoperative infections in elective teeth removal. Odontogenic infection, teeth removal, antibiotic use, prophylaxis, postoperative infection.

摘要

背景

本研究阐明了拔牙后严重感染患者的特征及院前护理情况。

材料与方法

本研究纳入了因拔牙后感染而住院的患者。比较了住院前接受择期拔牙和急性拔牙患者的背景变量及感染严重程度参数。此外,还评估了这些变量与抗生素使用之间的关联。

结果

在纳入研究的118例患者中,64%的拔牙原因是急性感染,36%是择期拔牙。从拔牙到住院的时间跨度差异很大(从<1天到205天)。先前急性拔牙的患者的时间差异明显大于择期拔牙的患者(=0.030)。吸烟与急性拔牙显著相关(<0.001)。择期组的住院时间(LOHS)长一天(=0.017)。总体而言,70%的患者在住院前接受了抗生素治疗。拔牙类型与抗生素使用之间存在显著关联(=0.005);择期拔牙患者使用抗生素的情况较少见。免疫功能低下的患者接受抗生素预防的频率明显高于非免疫功能低下的患者(=0.003)。LOHS与院前抗生素使用显著相关(=0.035)。未接受抗生素治疗的患者的LOHS比其他患者长一天。

结论

急性拔牙后很长一段时间可能会发生严重感染。应更加关注这些感染的前驱症状和早期有效治疗。更精确的抗生素使用时机可以减少择期拔牙术后的严重感染。牙源性感染、拔牙、抗生素使用、预防、术后感染。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b9b/8916597/ff4131247bc6/jced-14-e254-g001.jpg

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