Welter Laura, Bramke Silvia, May Christian Albrecht
Anatomisches Institut, Medizinische Fakultät Carl Gustav Carus, TU Dresden, Dresden, Germany.
Plast Reconstr Surg Glob Open. 2022 Mar 18;10(3):e4200. doi: 10.1097/GOX.0000000000004200. eCollection 2022 Mar.
Due to its clinical importance and due to a suggestion regarding the afferent innervation, the microscopic appearance of the frontalis muscle was investigated.
From seven human cadavers, serial sections of the frontalis muscle were studied using light microscopy. Immunhistochemistry was performed using antibodies against collagen XXII and neurofilament.
The macroscopic appearance of the muscle was in accordance with the literature. At both insertion sides, the muscle fiber endings expressed collagen XXII, a marker for myotendinous junctions, although no tendons were present at the origin side. Neuromuscular junctions were seen in the middle part of the muscle belly (insertion of the nerve fibers of the facialis nerve) and in the cranial part toward the galea aponeurotica (possible afferent fibers?).
This study summarizes the microscopic appearance of the frontalis muscle. It is a first example that collagen XXII can be expressed even without tendon formation. It confirms the absence of corpuscular afferent neuronal structures within the muscle.
鉴于额肌的临床重要性以及有关传入神经支配的一项建议，对额肌的微观外观进行了研究。
从七具人类尸体获取额肌的连续切片，使用光学显微镜进行研究。采用抗胶原蛋白XXII和神经丝的抗体进行免疫组织化学分析。
该肌肉的宏观外观与文献相符。在两侧附着处，肌纤维末端表达胶原蛋白XXII，这是肌腱结合处的标志物，尽管在起始侧不存在肌腱。在肌腹中部（面神经纤维的附着处）以及朝向帽状腱膜的颅部（可能是传入纤维？）可见神经肌肉接头。
本研究总结了额肌的微观外观。这是首个即使在未形成肌腱的情况下胶原蛋白XXII也能表达的实例。它证实了肌肉内不存在球状传入神经元结构。
