Department of Animal Nutrition and Forage Production, Mendel University in Brno, Brno, Czech Republic.
Department of Animal Morphology, Physiology and Genetics, Mendel University in Brno, Brno, Czech Republic.
J Equine Vet Sci. 2022 Jun;113:103937. doi: 10.1016/j.jevs.2022.103937. Epub 2022 Mar 19.
Milk thistle (Silybum marianum) provides several possible benefits for horses, namely anti-inflammatory, antioxidant effects, hepatoprotective, and neuroprotective effects. Silybin exerts also pronounced effects on energy metabolism, that could be useful for sport horses. The aim of this study is to evaluate the effect of milk thistle seed cakes (in the form of a granulated mixture with barley) on blood biochemical parameters (total protein, albumin, bilirubin, urea, creatinine, ALT, AST, ALP, GGT, LDH, the total cholesterol, HDL-cholesterol, LDL-cholesterol, TAG, BHB, NEFA, creatine kinase, lactate, glucose, glutathione peroxidase, total antioxidant capacity, cortisol, calcium, and phosphorus) to monitor the differences between the experimental (milk thistle in feed) and control horses after exposure of the monitored horses to heavy physical exercise (combined driving) total number of horses was 12 Czech Warmblood breed horses. The digestibility of silymarin (and its individual flavonolignans) and basic nutrients are also monitored in this study. Statistically significant differences (P < .05) were found mainly in plasma cortisol and NEFA levels. The results of this study confirmed the results of our previous studies. These results suggest that the feeding of milk thistle seed cakes has a possible positive effect on horse health and energy metabolism.
水飞蓟（Silybum marianum）可为马匹带来多种益处，例如抗炎、抗氧化、护肝和护脑作用。水飞蓟宾还对能量代谢有显著影响，这对运动马可能是有益的。本研究旨在评估水飞蓟籽饼（以大麦颗粒混合物的形式）对血液生化参数（总蛋白、白蛋白、胆红素、尿素、肌酐、ALT、AST、ALP、GGT、LDH、总胆固醇、HDL-胆固醇、LDL-胆固醇、TAG、BHB、NEFA、肌酸激酶、乳酸、葡萄糖、谷胱甘肽过氧化物酶、总抗氧化能力、皮质醇、钙和磷）的影响，以监测暴露于监测马匹剧烈体力活动（综合驾驶）后的实验（饲料中水飞蓟）和对照马匹之间的差异，共监测了 12 匹捷克温血马。本研究还监测了水飞蓟素（及其个别黄酮木脂素）和基本营养素的消化率。主要在血浆皮质醇和 NEFA 水平上发现了具有统计学意义的差异（P <.05）。本研究的结果证实了我们之前的研究结果。这些结果表明，喂食水飞蓟籽饼可能对马的健康和能量代谢有积极影响。
