McDaniel Charles, Bell Ruth, Farha Natalie, Vozzo Catherine, Bullen Jennifer, Rosen Michael, Romero-Marrero Carlos, Partovi Sasan, Kapoor Baljendra
Department of Internal Medicine, Cleveland Clinic, Cleveland, Ohio, USA.
Department of Internal Medicine, Cleveland Clinic, Cleveland, Ohio, USA
BMJ Open Gastroenterol. 2022 Mar;9(1). doi: 10.1136/bmjgast-2022-000876.
Transjugular intrahepatic portosystemic shunt (TIPS) placement is used to treat the sequelae of portal hypertension, including refractory variceal bleeding, ascites and hepatic hydrothorax. However, hernia-related complications such as incarceration and small bowel obstruction can occur after TIPS placement in patients with pre-existing hernias. The aim of this study was to determine the incidence of hernia complications in the first year after TIPS placement and to identify patient characteristics leading to an increased risk of these complications.
This retrospective analysis included patients with pre-existing abdominal hernias who underwent primary TIPS placement with covered stents at our institution between 2004 and 2018. The 1-year hernia complication rate and the average time to complications were documented. Using a Wilcoxon rank-sum test, the characteristics of patients who developed hernia-related complications versus the characteristics of those without complications were compared.
A total of 167 patients with pre-existing asymptomatic abdominal hernias were included in the analysis. The most common reason for TIPS placement was refractory ascites (80.6%). A total of 36 patients (21.6%) developed hernia-related complications after TIPS placement, including 20 patients with acute complications and 16 with non-acute complications. The mean time to presentation of hernia-related complications was 66 days. Patients who developed hernia-related complications were more likely than those without complications to have liver cirrhosis secondary to alcohol consumption (p=0.049), although this association was no longer significant after multivariate analysis.
Within 1 year after TIPS placement, approximately 20% of patients with pre-existing hernias develop hernia-related complications, typically within the first 2 months after the procedure. Patients with pre-existing hernia undergoing TIPS placement should be educated regarding the signs and symptoms of hernia-related complications, including incarceration and small bowel obstruction.
经颈静脉肝内门体分流术(TIPS)置入用于治疗门静脉高压的后遗症,包括难治性静脉曲张出血、腹水和肝性胸水。然而,在已有疝气的患者中,TIPS置入后可能会出现与疝气相关的并发症,如嵌顿和小肠梗阻。本研究的目的是确定TIPS置入后第一年疝气并发症的发生率,并确定导致这些并发症风险增加的患者特征。
这项回顾性分析纳入了2004年至2018年期间在我们机构接受带覆膜支架的初次TIPS置入的已有腹部疝气的患者。记录了1年疝气并发症发生率和并发症发生的平均时间。使用Wilcoxon秩和检验,比较了发生与疝气相关并发症的患者特征与未发生并发症患者的特征。
共有167例已有无症状腹部疝气的患者纳入分析。TIPS置入的最常见原因是难治性腹水(80.6%)。共有36例患者(21.6%)在TIPS置入后出现与疝气相关的并发症,包括20例急性并发症患者和16例非急性并发症患者。与疝气相关并发症出现的平均时间为66天。发生与疝气相关并发症的患者比未发生并发症的患者更可能有酒精性肝硬化(p=0.049),尽管多变量分析后这种关联不再显著。
在TIPS置入后1年内,约20%已有疝气的患者会出现与疝气相关的并发症,通常在术后前2个月内。应告知已有疝气并接受TIPS置入的患者有关与疝气相关并发症的体征和症状,包括嵌顿和小肠梗阻。